Research Topic

The Use and Abuse of Androgens

About this Research Topic

The use of androgens is common, and is a concern for many practitioners. While they are mainly prescribed for men in circumstances such as pubertal induction and late onset hypogonadism, androgens are also taken by women, especially in the treatment of some sexual disorders, such as reduced libido.

Prescription protocols are not always the same amongst practitioners. As such, it is difficult to assess benefits and side effects, especially in the case of long-term use. Some reported side-effects have included metabolic disorders, the increased incidence of fractures, and cardiovascular diseases, but also tumors including prostate and breast cancers.

Furthermore, more and more people, especially young men, have being using (or misusing) androgens in order to increase their muscular volume and improve their physical performance. However, the long-term consequences of such use and abuse of androgens is unknown, especially in terms of fertility.

In keeping with the scope and mission of Frontiers in Reproductive Health, this Research Topic aims to provide a multi-disciplinary platform for challenges and breakthroughs in each specialty that has led to a greater understanding of consequences of the use and abuse of androgens in men and women.

The following contributions are welcomed, but not limited to:

a) Perspectives - on androgens treatment & the need for standards of care in men and women.

b) Mini-reviews - highlighting the benefits of androgens therapy in men and in women, but also the side effects at short and long-term, including fertility disorders, cardiovascular diseases, metabolic disorders, fractures and tumors (prostate, breast), psychosexual issues affecting men and women. The consequences of doping, even in young men and women, could also be reported.

c) Original Research - on hormone manipulation and their direct and indirect consequences.

d) Commentaries - related to the indeterminate duration and routes of androgens therapy. Should we be concerned?


Keywords: androgens, testosterone, supplementation, doping, misuse, side effects, benefits, fertility, hypogonadism


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

The use of androgens is common, and is a concern for many practitioners. While they are mainly prescribed for men in circumstances such as pubertal induction and late onset hypogonadism, androgens are also taken by women, especially in the treatment of some sexual disorders, such as reduced libido.

Prescription protocols are not always the same amongst practitioners. As such, it is difficult to assess benefits and side effects, especially in the case of long-term use. Some reported side-effects have included metabolic disorders, the increased incidence of fractures, and cardiovascular diseases, but also tumors including prostate and breast cancers.

Furthermore, more and more people, especially young men, have being using (or misusing) androgens in order to increase their muscular volume and improve their physical performance. However, the long-term consequences of such use and abuse of androgens is unknown, especially in terms of fertility.

In keeping with the scope and mission of Frontiers in Reproductive Health, this Research Topic aims to provide a multi-disciplinary platform for challenges and breakthroughs in each specialty that has led to a greater understanding of consequences of the use and abuse of androgens in men and women.

The following contributions are welcomed, but not limited to:

a) Perspectives - on androgens treatment & the need for standards of care in men and women.

b) Mini-reviews - highlighting the benefits of androgens therapy in men and in women, but also the side effects at short and long-term, including fertility disorders, cardiovascular diseases, metabolic disorders, fractures and tumors (prostate, breast), psychosexual issues affecting men and women. The consequences of doping, even in young men and women, could also be reported.

c) Original Research - on hormone manipulation and their direct and indirect consequences.

d) Commentaries - related to the indeterminate duration and routes of androgens therapy. Should we be concerned?


Keywords: androgens, testosterone, supplementation, doping, misuse, side effects, benefits, fertility, hypogonadism


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

09 August 2021 Abstract
07 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

09 August 2021 Abstract
07 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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