Research Topic

Health Technology Assessment (HTA) of Innovations for Infectious Disease Prevention and Treatment to Inform Future Public Health Investments

About this Research Topic

The health and economic impact of the COVID-19 pandemic is in many aspects very impactful and exposes healthcare, societies, and economies to long-term burden. This emergency situation has shown how vulnerable we can be in outbreak situations and how important infectious disease preparedness and prevention are. Outbreaks from viruses and bacterial infections, as well as seasonal peaks of infectious diseases are not new, but the current impact is unprecedented high. This shows how individuals and populations are exposed to risks associated with infectious diseases. Therefore, it is very important to invest in pandemic preparedness, as well as the prevention and treatment of infectious diseases. This may require a more proactive decision-making approach by Health Technology Assessment (HTA) bodies.

HTA guided decision-making concerning the prevention and treatment of infectious diseases is not limited to technical aspects, but also largely influenced by political and societal considerations. These considerations often introduce additional complexity to inform decision-making surrounding public investments in infectious disease prevention under the uncertainty of the risk and impact of the disease. Cost-effectiveness – as one of the decision-making criteria – may not incorporate all values of innovations. In particular, the values captured by applying broader public health, societal and macro-economic perspectives are currently not broadly included. Therefore, the aim of this Research Topic proposal is to address the role of HTA to inform future public health investments in innovations for infectious disease prevention and treatment.

Topics of interest include, but are not limited to:

- Systematic reviews and conceptual articles on sustainable HTA frameworks equipped to inform early research and development investments and public health decision-making

- Articles that address important methodological aspects of early HTA, health economic evaluation, and infectious disease modelling in the context of healthcare decision making frameworks

- Original articles on the cost-effectiveness of infectious disease prevention and treatment to conduct early, adaptive, and living HTA’s

- Innovative ways of presenting the clinical and economic value of innovations for infectious disease prevention and treatment by applying broader public health, societal and economic perspective (eg, budget optimization, fiscal modelling, option value methods, etc)


Keywords: cost-effectiveness, preparedness, prevention, treatment, investment


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

The health and economic impact of the COVID-19 pandemic is in many aspects very impactful and exposes healthcare, societies, and economies to long-term burden. This emergency situation has shown how vulnerable we can be in outbreak situations and how important infectious disease preparedness and prevention are. Outbreaks from viruses and bacterial infections, as well as seasonal peaks of infectious diseases are not new, but the current impact is unprecedented high. This shows how individuals and populations are exposed to risks associated with infectious diseases. Therefore, it is very important to invest in pandemic preparedness, as well as the prevention and treatment of infectious diseases. This may require a more proactive decision-making approach by Health Technology Assessment (HTA) bodies.

HTA guided decision-making concerning the prevention and treatment of infectious diseases is not limited to technical aspects, but also largely influenced by political and societal considerations. These considerations often introduce additional complexity to inform decision-making surrounding public investments in infectious disease prevention under the uncertainty of the risk and impact of the disease. Cost-effectiveness – as one of the decision-making criteria – may not incorporate all values of innovations. In particular, the values captured by applying broader public health, societal and macro-economic perspectives are currently not broadly included. Therefore, the aim of this Research Topic proposal is to address the role of HTA to inform future public health investments in innovations for infectious disease prevention and treatment.

Topics of interest include, but are not limited to:

- Systematic reviews and conceptual articles on sustainable HTA frameworks equipped to inform early research and development investments and public health decision-making

- Articles that address important methodological aspects of early HTA, health economic evaluation, and infectious disease modelling in the context of healthcare decision making frameworks

- Original articles on the cost-effectiveness of infectious disease prevention and treatment to conduct early, adaptive, and living HTA’s

- Innovative ways of presenting the clinical and economic value of innovations for infectious disease prevention and treatment by applying broader public health, societal and economic perspective (eg, budget optimization, fiscal modelling, option value methods, etc)


Keywords: cost-effectiveness, preparedness, prevention, treatment, investment


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

24 August 2021 Abstract
22 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

24 August 2021 Abstract
22 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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