About this Research Topic
Modern Obstetrics are running towards prevention of complications. Three levels of prevention can be programmed, represented by primary, secondary, or tertiary prevention of pregnancy complications. The best strategies are those allowing to achieve the first two levels of prevention. Therefore, it is crucial to design studies addressing the question of how the placenta changes in the presence of pathologic conditions of pregnancy, in order to understand the pathophysiology of placental disorders associated with pregnancy complications, and prevent their negative maternal and fetal/neonatal outcomes. Several authors have tried to address this task, although more studies need to be performed.
The present research topic aims to convey retrospective and prospective studies, as well as systematic reviews of the literature, assessing potential association of placental alterations and changes with obstetric complications. In addition, studies analyzing the pathophysiology and the molecular basis of the mechanisms leading to adverse outcomes of pregnancy would be of great interest to the topic.
Keywords: Placenta, Great Obstetrical Syndromes, Preterm labor, PROM, Chorioamnionitis, Gestational diabetes mellitus, IUGR, Fetal demise
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.