About this Research Topic
Approximately 2 million people die from lower respiratory tract infections each year. Respiratory viral infections have long been overlooked in immunocompetent adults. In recent years, new types of respiratory viruses have continued to emerge. Intermittent outbreaks of respiratory viral infectious diseases represented by pandemic H1N1 influenza, avian influenza H7N9, and SARS-CoV-2 have seriously threatened people's health and public safety. However, there is still a lack of the comprehensive studies in epidemiology of viral infections in immunocompetent adults.
Respiratory viral infection in immunocompetent adults normally leads to mild illness, but could also results in severe lung injury and even death in some patients. Except for direct attack by the virus, dysregulation of immune response is also involved in the pathogenesis. Though, it is acknowledged that the so-called “cytokine storm” fuelling some deaths of respiratory viral infection, the exact mechanism related, and the regulation was still underdetermined, and effective treatment are lacking.
In this Research Topic, we aim to provide an overview of recent progress in the epidemiology of respiratory viral infection in immunocompetent adults, including the disease burden and virus spectrum. More specifically, we hope to share the latest research results on the immune pathogenesis of viral pneumonia and effective treatments.
This Research Topic welcomes Research Articles, Mini Reviews and Reviews, on the following subtopics, but not limited to:
• Novel and exciting findings on epidemiology, mechanism of immune pathogenesis, treatment of viral respiratory infection in competent adults in the form of original research articles and Brief Research Reports.
• Reviews including meta-analysis assessing the epidemiology of respiratory viral infection in competent adults, including the disease burden and virus spectrum.
• Opinion and Perspective pieces from experts in this filed to discuss the current knowledge in the immune pathogenesis and potent intervention targets of viral pneumonia in immunocompetent adults.
Keywords: Respiratory virus, infection, epidemiology, mechanism, management
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.