About this Research Topic
Nowadays, stress may be considered as a pivotal aspect in aquaculture as many stressors can change biological homeostasis, which then affects fish growth, health and even survival. Water dissolved oxygen levels are one of the key environmental variables for the survival of aquatic organisms under intensive aquaculture production, which is easily affected by natural and man-made changes to environments such as high temperature, water eutrophication, industrial wastewater discharge, and high-density aquaculture. Normally, stressors such as hypoxia induced extra energy requirements leading to the depletion of energy stores in fish. Although hormone mediating the physiological stress response is clear now, the effects of hypoxia and other concurrent stressors on fish energy mobilization are still needed to be investigated in cultured fish. This energy mobilization might be modulated by AMPK/mTOR signaling pathway then leading to glucose and lipid metabolism regulation.
The aim of this Research Topic is to provide physiological modulation stimulated by stress, as well as to underlie energy metabolism regulation stimulated by stress in fish. It has been reported that AMPK signaling pathway and insulin signaling pathway are involved in glucose and lipid utilization in fish exposed to hypoxia exposure. Thus, the roles of hormones in mediating the stress effects in the modification of metabolism are very important. However, an integrated regulatory network of pathways involved in fish in response to a stressor is not clear. To elucidate the mechanism of the energy regulation in fish responses to stress and stressor will be helpful for us to understand the adaption on stress in fish.
1) Homeostasis modifications caused by stress
2) Hormone function and mechanisms in mediating the stress effects
3) Energy metabolism modulation stimulated by stress
The aim of this Research Topic is to provide physiological modulation stimulated by stress, as well as to underlie energy metabolism regulation stimulated by stress in fish. It has been reported that AMPK signaling pathway and insulin signaling pathway are involved in glucose and lipid utilization in fish exposed to hypoxia exposure. Thus, the roles of hormones in mediating the stress effects in the modification of metabolism are very important. However, an integrated regulatory network of pathways involved in fish in response to a stressor is not clear. To elucidate the mechanism of the energy regulation in fish responses to stress and stressor will be helpful for us to understand the adaption on stress in fish.
1) Homeostasis modifications caused by stress
2) Hormone function and mechanisms in mediating the stress effects
3) Energy metabolism modulation stimulated by stress
Keywords: Glucose metabolism, Lipid metabolism, Signaling pathway, Stress, Fish
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
