About this Research Topic
The gut microbiome plays an incredibly profound role in human health. The primary function of the diverse microbial community includes improving our digestion, producing different metabolites, and activating our immune system. Chronic respiratory diseases (CRD) are multifactorial diseases that are considered as a severe public health problem throughout the world. A growing body of evidence shows that the immune system plays a central role in the development of CRD. CRD encompass a broad range of common inflammatory respiratory conditions including asthma, COPD (chronic obstructive pulmonary disease), bronchiectasis, and other obstructive bronchial processes.
Probiotics, prebiotics and postbiotics have been widely used to treat respiratory diseases, but their clinical effect has not been thoroughly investigated. Meanwhile, microbial clinical efficacy for CRD varies across the strains, highlighting the importance of exploring different candidate strains and their metabolites. Different precision strains can be applied to deal with individualized gut microbiome in clinic. Hence, immunological research on human microbiome not only reveals the mechanisms that underlie the diseases, but also suggests new therapies that may minimize the morbidity and mortality.
This Research Topic aims to understand the effect of probiotics, prebiotics and postbiotics on intestinal permeability, intestinal microbial composition, and the regulation of certain metabolites in the treatment and prevention of CRD. It also highlights the latest research that relates probiotics, prebiotics, postbiotics and gut microbiota to the development of the inflammatory process in CRD. We welcome manuscripts of different types (e.g., Original Research, Perspectives, Minireviews, Commentaries and Opinion Papers) from, but not limited to, the following subtopics:
• Probiotics, prebiotics and postbiotics and host immunity, and their relationship with gut microbiota therapeutic modulation in CRD
• Effect of probiotics, prebiotics and postbiotics on remote organs and immune system in CRD treatment
• Intervention studies of probiotics, prebiotics and postbiotics on CRD
• Novel probiotics, prebiotics and postbiotics in the treatment of CRD
• Other new insights of probiotics, prebiotics and postbiotics in CRD
Probiotics, prebiotics and postbiotics have been widely used to treat respiratory diseases, but their clinical effect has not been thoroughly investigated. Meanwhile, microbial clinical efficacy for CRD varies across the strains, highlighting the importance of exploring different candidate strains and their metabolites. Different precision strains can be applied to deal with individualized gut microbiome in clinic. Hence, immunological research on human microbiome not only reveals the mechanisms that underlie the diseases, but also suggests new therapies that may minimize the morbidity and mortality.
This Research Topic aims to understand the effect of probiotics, prebiotics and postbiotics on intestinal permeability, intestinal microbial composition, and the regulation of certain metabolites in the treatment and prevention of CRD. It also highlights the latest research that relates probiotics, prebiotics, postbiotics and gut microbiota to the development of the inflammatory process in CRD. We welcome manuscripts of different types (e.g., Original Research, Perspectives, Minireviews, Commentaries and Opinion Papers) from, but not limited to, the following subtopics:
• Probiotics, prebiotics and postbiotics and host immunity, and their relationship with gut microbiota therapeutic modulation in CRD
• Effect of probiotics, prebiotics and postbiotics on remote organs and immune system in CRD treatment
• Intervention studies of probiotics, prebiotics and postbiotics on CRD
• Novel probiotics, prebiotics and postbiotics in the treatment of CRD
• Other new insights of probiotics, prebiotics and postbiotics in CRD
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
