Research Topic

Neurodevelopmental Outcomes After Neonatal and Infant Cardiac Surgery Using Cardiopulmonary

About this Research Topic

Neurodevelopmental delay or developmental disabilities after neonatal or infant cardiac surgery are more common than expected. Preoperatively, structural brain immaturity has already pointed out in neonates with congenital heart disease. Intraoperatively, cardiopulmonary bypass conditions, anesthesia management and technical performance have been modified. Postoperatively, safe intensive care unit management has been advocated. From the birth to after surgery, many efforts have been made, but no obvious factor is pointed out and those outcomes might be caused multifactorially. Although many efforts have been applied to reduce mortality or morbidities after neonatal or infant cardiac surgery, we should focus on improving neurodevelopmental outcomes as well.



This Research Topic will look at next step to improve the quality of life in survivors after neonatal or infant cardiac surgery, accumulating the recent advances in the field; e.g. rehabilitation program to stimulate patients’ developmental course.



Although the cause of neurodevelopmental delay or developmental disabilities are multifactorial, we should focus on those struggling with these problems. In this Research Topic, we welcome recent advances on postoperative management to improve patients’ quality of life.


Keywords: Neurodevelopmental outcome, Bayley scale, congenital heart disease, surgery, cardiopulmonary


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Neurodevelopmental delay or developmental disabilities after neonatal or infant cardiac surgery are more common than expected. Preoperatively, structural brain immaturity has already pointed out in neonates with congenital heart disease. Intraoperatively, cardiopulmonary bypass conditions, anesthesia management and technical performance have been modified. Postoperatively, safe intensive care unit management has been advocated. From the birth to after surgery, many efforts have been made, but no obvious factor is pointed out and those outcomes might be caused multifactorially. Although many efforts have been applied to reduce mortality or morbidities after neonatal or infant cardiac surgery, we should focus on improving neurodevelopmental outcomes as well.



This Research Topic will look at next step to improve the quality of life in survivors after neonatal or infant cardiac surgery, accumulating the recent advances in the field; e.g. rehabilitation program to stimulate patients’ developmental course.



Although the cause of neurodevelopmental delay or developmental disabilities are multifactorial, we should focus on those struggling with these problems. In this Research Topic, we welcome recent advances on postoperative management to improve patients’ quality of life.


Keywords: Neurodevelopmental outcome, Bayley scale, congenital heart disease, surgery, cardiopulmonary


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 October 2021 Abstract
28 February 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 October 2021 Abstract
28 February 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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