About this Research Topic
Ischemic stroke is a prevalent neurological disorder with high morbidity, mortality, and recurrence rate. It can result in long-term disability, which has an impact on patients’ physical and mental health, and poses a heavy financial burden on their families and society. The prevention and treatment of ischemic stroke is an important issue to be addressed urgently.
Due to the narrow time window of treatment efficacy after stroke, a large majority of stroke patients are unresponsive or resistant to treatment. Therefore, further research is required to develop a safe, effective, and easy-to-apply treatment for stroke. In recent years, new technology approaches have shown to be promising for tackling difficult problems related to neurological disorders. The advancement and application of biomaterials such as hydrogels, nanoparticles, and stents have greatly boosted the understanding of the pathogenesis of ischemic stroke as well as the development of novel ischemic stroke treatment approaches. For example, nanoparticles can deliver drugs directly to the thrombus and effectively remove the thrombus, and the hydrogel can continuously release embedded drugs to repair the damaged central nervous system. The research and development of new biomaterials play a crucial role in promoting cell therapy.
This research topic aims to better understand the neural mechanisms underlying the ischemic stroke prevention and treatment function of new biomaterials. We welcome submissions from multidisciplinary research aimed at elucidating underlying cellular and molecular mechanisms of the roles of novel biomaterials in the prevention and treatment of ischemic stroke.
Authors are encouraged to submit original research articles, reviews, commentaries, mini-reviews, and perspective articles, including but are not limited to the following subtopics:
- Study the key mechanism of new biomaterials in the prevention and treatment of ischemic stroke.
- Investigate the role of new biomaterials in improving neurological functions and treating neurological deficits.
Keywords: Ischemic stroke, Cerebrovascular dysfunction, Neurological function, Biomaterials, Neuroprotection, Treatment strategies
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.