About this Research Topic
Clostridium difficile (C. difficile) is a leading pathogen which causes antibiotic-associated diarrhea and colitis. Global epidemics of Clostridium difficile infections (CDI) have shown that C. difficile is frequently transmitted between continents. The epidemiology of CDI has been well documented in North America and Europe, and C. difficile from these regions has been studied in detail. However, there have been only some studies on CDI in the Asia-Pacific region and the few that have been conducted have suggested unique characteristics to CDI in this region compared to others. Thus, the time is now right to arrange a Research Topic to present and highlight these novel findings.
This Research Topic will provide a historical overview of CDI in general, as well as summarize genomic, epidemiology and clinical features of CDI in the Asia-Pacific region. Of great interest are also country-specific epidemiology and clinical feature papers from South Korea, Japan, China/Taiwan/Hong Kong, Thailand, India, and Malaysia/Indonesia.
The papers in this Research Topic will present authoritative works on country-specific C. difficile incidence and epidemiology in the Asia-Pacific region. We seek an interdisciplinary approach, with authors acting as researchers in academic institutes, centers for disease control, and hospitals, as well as those who work in fields including environmental, veterinary, molecular, and clinical microbiology. We welcome papers from leading researchers in the fields of the following themes:
• Articles providing a historical overview of CDI in general
• Genomic epidemiology studies on CDI in the Asia-Pacific region
• Review papers on clinical features of CDI in the Asia-Pacific region
• Country specific original research on CDI in the Asia-Pacific region
• Reviews and perspectives on antimicrobial resistance and control in both humans and animals
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.