Outbreaks and prevalence of foodborne diseases in humans caused by pathogenic bacteria endanger global healthcare systems, and adversely affect economic growth and social stability. Along with the rapid development of web-based and mobile-ready electronic commerce, the fast-paced national and international trades in foodstuffs around the globe present new challenges to food safety systems, particularly in developing nations. Pathogenic bacteria contaminate various foods at any stage in the entire food chain. The most commonly known bacterial pathogens associated with foodborne diseases worldwide are Salmonella enterica, Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, Cronobacter sakazakii, Vibrio cholerae, and Vibrio parahaemolyticus. Foodborne diseases are one of the major contributors to global human disease burden and mortality. Thus, a better understanding of their pathogenic mechanisms is imperative to eliminate and control pathogen persistence in foods and resistant infections in humans.
Although numerous virulence factors in foodborne bacterial pathogens have been characterized, molecular mechanisms underlying how various food matrixes and environment stimuli modulate secretion systems and virulent effectors of pathogenic bacteria; how pathogenic bacteria are manipulated by host environments, and interact with host cells, and resident alimentary or respiratory tract microbiota; and how host immune systems response against the infection of pathogenic bacteria remain to be fully elucidated. New compounds and treatment strategies for the effective control of pathogenic bacteria are needed in further research.
This Research Topic is focused on novel findings, and current advances in such exciting research field, for scientists, governments, food producers, food suppliers, and food consumers, in molecular mechanisms underlying infection and control of foodborne pathogenic bacteria that pose emergency threats to the public health for humans and consumable animals, particularly in globalization background. We welcome authors around the world to contribute high-quality original research articles as well as review articles in this Research Topic that include, but are not limited to the specific themes listed below:
• Emerging foodborne pathogenic bacteria and their virulence and genetic diversity;
• How various food matrixes and environment stimuli modulate secretion systems and virulent effectors of foodborne pathogenic bacteria;
• How motility, adhesion, invasion or apoptosis of foodborne pathogenic bacteria are manipulated by host environments;
• How foodborne pathogenic bacteria interact with host cells, and resident alimentary or respiratory tract microbiota;
• How host immune systems respond against the infection of foodborne pathogenic bacteria.
• New compounds and treatment strategies for the control of foodborne pathogenic bacteria.
Outbreaks and prevalence of foodborne diseases in humans caused by pathogenic bacteria endanger global healthcare systems, and adversely affect economic growth and social stability. Along with the rapid development of web-based and mobile-ready electronic commerce, the fast-paced national and international trades in foodstuffs around the globe present new challenges to food safety systems, particularly in developing nations. Pathogenic bacteria contaminate various foods at any stage in the entire food chain. The most commonly known bacterial pathogens associated with foodborne diseases worldwide are Salmonella enterica, Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, Cronobacter sakazakii, Vibrio cholerae, and Vibrio parahaemolyticus. Foodborne diseases are one of the major contributors to global human disease burden and mortality. Thus, a better understanding of their pathogenic mechanisms is imperative to eliminate and control pathogen persistence in foods and resistant infections in humans.
Although numerous virulence factors in foodborne bacterial pathogens have been characterized, molecular mechanisms underlying how various food matrixes and environment stimuli modulate secretion systems and virulent effectors of pathogenic bacteria; how pathogenic bacteria are manipulated by host environments, and interact with host cells, and resident alimentary or respiratory tract microbiota; and how host immune systems response against the infection of pathogenic bacteria remain to be fully elucidated. New compounds and treatment strategies for the effective control of pathogenic bacteria are needed in further research.
This Research Topic is focused on novel findings, and current advances in such exciting research field, for scientists, governments, food producers, food suppliers, and food consumers, in molecular mechanisms underlying infection and control of foodborne pathogenic bacteria that pose emergency threats to the public health for humans and consumable animals, particularly in globalization background. We welcome authors around the world to contribute high-quality original research articles as well as review articles in this Research Topic that include, but are not limited to the specific themes listed below:
• Emerging foodborne pathogenic bacteria and their virulence and genetic diversity;
• How various food matrixes and environment stimuli modulate secretion systems and virulent effectors of foodborne pathogenic bacteria;
• How motility, adhesion, invasion or apoptosis of foodborne pathogenic bacteria are manipulated by host environments;
• How foodborne pathogenic bacteria interact with host cells, and resident alimentary or respiratory tract microbiota;
• How host immune systems respond against the infection of foodborne pathogenic bacteria.
• New compounds and treatment strategies for the control of foodborne pathogenic bacteria.
