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There is strong evidence to suggest that diet and nutrition can benefit human brain health in numerous ways across a wide range of healthy and clinical populations through various outcome measures, for example cognitive function, mood, and neurodegenerative disease. This evidence base consists of, ...

There is strong evidence to suggest that diet and nutrition can benefit human brain health in numerous ways across a wide range of healthy and clinical populations through various outcome measures, for example cognitive function, mood, and neurodegenerative disease. This evidence base consists of, observational studies, epidemiological trials and acute and chronic interventions such as randomized controlled trials. Despite the strength of the evidence base, less is known about the mechanisms and pathways of action than may explain the reported associations between nutrition and brain health.

Many published studies demonstrating nutritional benefits to the human brain do not consider or offer a possible pathway by which the nutrient, food group or dietary approach may exert its effects on the brain. The purpose of this Research Topic is to bring together current evidence and opinions relating to the mechanisms and pathways of action for nutritional effects on brain health. This would enhance the field by giving a greater understanding of how we can utilize nutritional approaches to enhance brain health.

We welcome contributions which:
(i) Provide data exploring possible mechanisms of action and pathways in this field.
(ii) Provide a systematic overview of mechanisms or pathways in this field.

The contributions should be clearly relevant to mechanisms and pathways present in humans. Data from animals models will be considered providing it shows clear relevance to humans.

Both Dr. Lamport and Dr. Williams have received research grants from various private companies.

Keywords: Mechanisms, Nutrition, Brain Health, Cognition, Cerebral Blood Flow


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