Research Topic

Stress related effects on brain function and sensitivity to ethanol: role of receptor systems and neuromodulators

  • Submission closed.

About this Research Topic

Stress-related effects are now considered a real disease that strongly alters the individual life style. In the last decades a tremendous amount of research has been devoted to exploring in great details the possible molecular mechanisms involved in the stress-related physiopathological responses, as well as ...

Stress-related effects are now considered a real disease that strongly alters the individual life style. In the last decades a tremendous amount of research has been devoted to exploring in great details the possible molecular mechanisms involved in the stress-related physiopathological responses, as well as the role of stress as a predisposing factor for abuse of psychotropic substances including ethanol. Improvement of various techniques in several fields such as electrophysiology, molecular biology and pharmacology, has greatly contributed to the discovery of the role of specific molecular targets involved in stress and ethanol actions. Thus a complex interplay mechanisms have emerged where different receptor and various neuromodulator systems (i.e., cholesterol-derived neuroactive steroids, BDNF, CRF, endocannabinoids, and others) are often associated to stress- and ethanol-related responses. Alterations in the activity of these molecular players, in turn, could be highly associated with profound changes in neuronal physiology and synaptic plasticity hampering the function of selective brain areas directly involved in the control of anxiety-like behaviors, reward-related effects, learning and memory. The goal of this Research Topic will be directed to collect different and most recent points of view arising from all major expertise in the field of ethanol and stress regarding the potential molecular mechanisms through which stress affects brain physiology that may be relevant for the increased ethanol abuse in stressed individuals. This Topic Section may provide exciting novel experimental results that may contribute to more unified understanding of the role played by distinct brain areas in the response to stress and ethanol actions.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top