Over the past decade there has been an increasingly recognized epidemic of Human Papillomavirus related Oropharyngeal Squamous Cell Carcinoma (HPV-positive OPSCC). HPV-positive OPSCC is characterized by a better prognosis and more favorable response to therapy when compared to its HPV-negative counterpart. Multiple clinical trials are now aimed at de-intensifying treatment for HPV-positive OPSCC, with the aims being to preserve swallowing function after surgical intervention and reduce the morbidity of treatment while maintaining a high rate of cure. Innovations in surgical management which include the development of Transoral Robotic Surgery (TORS), as well as innovations and updates to intraoperative imaging, have each played a crucial role in enabling more effective curative treatment of this disease while preserving and maximizing quality of life in patients.
We seek to establish a solid reference on the current thoughts regarding surgical management of HPV-positive OPSCC. This will allow the consolidation of knowledge and will help clinicians to focus on providing the best possible care practices for this disease, thus improving patient prognoses and also enhancing postsurgical outcomes through refinement of current surgical strategies and implementation of new techniques and procedures.
This collection of articles will provide a comprehensive overview of the role of surgery in the management of HPV-positive OPSCC. This Research Topic welcome submissions addressing, but not limited to, the following topics surrounding the surgical management of HPV-Positive OPSCC ;
- Reviews of the latest technical innovations in transoral robotic surgery (TORS)
- An update in the surgical management of HPV-positive OPSCC of the neck with unknown primary site
- The role of surgery in clinical trials for HPV-OPSCC
- Intraoperative imaging in HPV-OPSCC
- A review of complications in TORS and how to manage them
Important Note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
Over the past decade there has been an increasingly recognized epidemic of Human Papillomavirus related Oropharyngeal Squamous Cell Carcinoma (HPV-positive OPSCC). HPV-positive OPSCC is characterized by a better prognosis and more favorable response to therapy when compared to its HPV-negative counterpart. Multiple clinical trials are now aimed at de-intensifying treatment for HPV-positive OPSCC, with the aims being to preserve swallowing function after surgical intervention and reduce the morbidity of treatment while maintaining a high rate of cure. Innovations in surgical management which include the development of Transoral Robotic Surgery (TORS), as well as innovations and updates to intraoperative imaging, have each played a crucial role in enabling more effective curative treatment of this disease while preserving and maximizing quality of life in patients.
We seek to establish a solid reference on the current thoughts regarding surgical management of HPV-positive OPSCC. This will allow the consolidation of knowledge and will help clinicians to focus on providing the best possible care practices for this disease, thus improving patient prognoses and also enhancing postsurgical outcomes through refinement of current surgical strategies and implementation of new techniques and procedures.
This collection of articles will provide a comprehensive overview of the role of surgery in the management of HPV-positive OPSCC. This Research Topic welcome submissions addressing, but not limited to, the following topics surrounding the surgical management of HPV-Positive OPSCC ;
- Reviews of the latest technical innovations in transoral robotic surgery (TORS)
- An update in the surgical management of HPV-positive OPSCC of the neck with unknown primary site
- The role of surgery in clinical trials for HPV-OPSCC
- Intraoperative imaging in HPV-OPSCC
- A review of complications in TORS and how to manage them
Important Note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.