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The animal microbiome—including bacteria, fungi, archaea, and viruses —are complex and diverse ecosystem. It is widely distributed among different biogeographical locations, such as the gastrointestinal system, respiratory system, reproductive system, and skin. It plays an important role in animal health but ...

The animal microbiome—including bacteria, fungi, archaea, and viruses —are complex and diverse ecosystem. It is widely distributed among different biogeographical locations, such as the gastrointestinal system, respiratory system, reproductive system, and skin. It plays an important role in animal health but is involved in protection against several animal diseases by providing colonization resistance against pathogens. The advancement of high-throughput technologies has propelled exponential increases in the understanding of the interaction between these microbes, their genetic material and their host. Metagenomic research are now offering a great opportunity to describe the dynamics of interactions between the host and mucosal microbiota which may influence or drive the infectious disease processes. Animal microbiome can be affected by various host and environmental factors, such as different management strategies, diet composition, physiological conditions and stress. Animal susceptibility to disease is intimately linked to composition and developmental dynamics of microbiome. The difference in the composition of the animal microbiome (Bacteriome, Mycobiome, Archaeome and Virome ) raises interesting questions in regard to the mechanisms of colonization resistance at different body locations. Therefore, it is of great importance to maintain the homeostasis of animal microbiome for proper health conditions and enhance animal immune function, and protection against pathogens. Manipulation of animal microbiome at different stages of the production cycle also represents an attractive proposition for animal production sector and has been suggested as a possible alternative to the use of antibiotics in the management of disease.

This Research Topic welcomes ongoing studies on the role of Bacteriome, Mycobiome, Archaeome and Virome in animal health and disease with an emphasis on their compositional changes associated with infectious diseases susceptibility (associative, correlative, or causal), and its potential role towards enhancing animal health and profitability.

Keywords: Colonization resistance, infectious disease, Microbiome, Bacteriome, Mycobiome, Archeome, Virome, Livestock, Sequencing


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