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With the rising aging population in a global range, related neuropsychiatric disorders such as depression and dementia, have emerged and caused a tremendous disease burden. Over the past decades, the understanding of neuropsychiatric disorders in the aging population has improved to a new extent. Many risk ...

With the rising aging population in a global range, related neuropsychiatric disorders such as depression and dementia, have emerged and caused a tremendous disease burden. Over the past decades, the understanding of neuropsychiatric disorders in the aging population has improved to a new extent. Many risk factors have been identified, and advances have been made in developing prevention and intervention strategies. However, there still exist challenges to be addressed. These challenges include but are not limited to early detection and prediction of neuropsychiatric disorders, comorbidities of both neuropsychiatric and non-neuropsychiatric aspects, identifying novel indicators for disease progression and prognosis, as well as investigating potential mediating mechanisms.

Facing unprecedented challenges, the research topic aims to promote healthy aging and longevity from the neuropsychiatric perspective, via collaboration from a number of professional disciplines. Implications from the topic will focus on guiding comprehensive care and best practice in preventing and managing major neuropsychiatric disorders of the aging population, such as depression or depressive symptoms, cognitive decline, cognitive impairment, and dementia.

This section welcomes a wide variety of researches in aging psychiatry, including community-based and hospital-based observational studies, interventional researches (such as RCTs), and systematic reviews and meta-analyses, but not fundamental researches, and intends to provide novel insights into preventing and managing neuropsychiatric disorders in the aging population. Studies on the following topics will be of special interest:

1) Disease burden of neuropsychiatric disorders and comorbidities in the aging population, as well as attributable risk factors.

2) Early detection and prediction of depression or depressive symptoms, cognitive impairment, and dementia.

3) Identifying novel indicators for neuropsychiatric disorders progression and prognosis, such as trajectories of cognitive decline.

4) Investigating potential mediating mechanisms regarding associations between risk factors and neuropsychiatric disorders incidence, progression, and prognosis.

5) Exploring effective interventions including health education, lifestyle intervention, and drugs on depression or depressive symptoms, cognitive impairment, and dementia.

Keywords: depression, dementia, cognitive decline, cognitive impairment, aging population


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