About this Research Topic
Metabolic syndrome is a major global health concern that is on the rise, with increasing rates of obesity, diabetes, and hyperlipidemia affecting most parts of the world. There is now an improved understanding of the association between metabolic syndrome and several inflammatory skin diseases. Dermatoses such as psoriasis, hidradenitis suppurativa, acne vulgaris, acanthosis nigricans are hypothesized to have strong pathologic links to metabolic syndrome. With this article series, we will discuss the common pathogenesis underlying these conditions, with an aim to attempt to improve prevention, recognition of underlying systemic conditions, optimize management of dermatoses, and guide future research.
This article series should serve to elucidate and simplify current research on pathogenesis. The complex interplay between the insulin signaling pathway, adipose hormones, and chronic inflammation underlying the development of chronic inflammatory dermatoses that are commonly associated with metabolic syndrome. The goal should also be to incorporate novel management options in development for these conditions.
The specific topics that need to be discussed are metabolic syndrome and psoriasis, hidradenitis, acne, atopic dermatitis, and androgenetic alopecia. These topics can be elucidated in terms of epidemiology, pathogenesis, and recent advances in management with a focus on potential therapeutic options targeting both the inflammation and metabolic derangements if any.
This article series should serve to elucidate and simplify current research on pathogenesis. The complex interplay between the insulin signaling pathway, adipose hormones, and chronic inflammation underlying the development of chronic inflammatory dermatoses that are commonly associated with metabolic syndrome. The goal should also be to incorporate novel management options in development for these conditions.
The specific topics that need to be discussed are metabolic syndrome and psoriasis, hidradenitis, acne, atopic dermatitis, and androgenetic alopecia. These topics can be elucidated in terms of epidemiology, pathogenesis, and recent advances in management with a focus on potential therapeutic options targeting both the inflammation and metabolic derangements if any.
Keywords: Metabolic syndrome, Psoriasis, Obesity, Hidradenitis, Acne
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