About this Research Topic
This Research Topic is part of the Model Organisms series of Frontiers in Physiology. Other titles in this series would be:
• Model Organisms: Opportunities and Challenges in Vascular Physiology
• Model Organisms: Opportunities and Challenges in Redox Physiology
• Model Organisms: Opportunities and Challenges in Avian Physiology
Model organisms have long been widely used in the field of biosciences, including a range of subject areas within physiology. Several important milestones have been achieved in the field thanks to their application, allowing scientists to develop concepts, technologies, and methodologies to better understand more complex living systems, including humans.
In addition to focusing on the many advantages of using model organisms in the field of Gastrointestinal Sciences, this Research Topic also aims to shed light on the challenges and limitations that accompany their application.
The scope of this collection covers, but is not limited to, the following themes and questions:
• Development of model in vitro organ systems for gut, liver and pancreas tissue.
• Validation of model vitro organ systems with established in vitro and in vivo models.
• Use of model systems to reveal function and dysfunction of gut, liver and pancreas tissue.
• Use of model systems to test the effects of mutations on function.
• Use of model organ systems to test interactions between one organ system and anther organ system (i.e., gut and liver interactions).
• Use of model systems to test effects of dietary constituents on function.
• Use of model systems to test effects of the microbiome and its metabolites.
• Use of model systems to test potential therapeutic agents.
Manuscripts submitted to this Research Topic should be in line with the scope of the Gastrointestinal Sciences section. Several article types will be considered, please find more information on the journal page.
• Model Organisms: Opportunities and Challenges in Vascular Physiology
• Model Organisms: Opportunities and Challenges in Redox Physiology
• Model Organisms: Opportunities and Challenges in Avian Physiology
Model organisms have long been widely used in the field of biosciences, including a range of subject areas within physiology. Several important milestones have been achieved in the field thanks to their application, allowing scientists to develop concepts, technologies, and methodologies to better understand more complex living systems, including humans.
In addition to focusing on the many advantages of using model organisms in the field of Gastrointestinal Sciences, this Research Topic also aims to shed light on the challenges and limitations that accompany their application.
The scope of this collection covers, but is not limited to, the following themes and questions:
• Development of model in vitro organ systems for gut, liver and pancreas tissue.
• Validation of model vitro organ systems with established in vitro and in vivo models.
• Use of model systems to reveal function and dysfunction of gut, liver and pancreas tissue.
• Use of model systems to test the effects of mutations on function.
• Use of model organ systems to test interactions between one organ system and anther organ system (i.e., gut and liver interactions).
• Use of model systems to test effects of dietary constituents on function.
• Use of model systems to test effects of the microbiome and its metabolites.
• Use of model systems to test potential therapeutic agents.
Manuscripts submitted to this Research Topic should be in line with the scope of the Gastrointestinal Sciences section. Several article types will be considered, please find more information on the journal page.
Keywords: gastrointestinal sciences, physiology, model organisms, ...
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
