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Cyclic adenosine monophosphate (cAMP) is a second messenger of paramount biological importance, involved in the regulation of a significant number of cellular functions through the cAMP-dependent intracellular signal transduction pathways. The aim of this “Frontiers in Pharmacology Research Topic” is to ...

Cyclic adenosine monophosphate (cAMP) is a second messenger of paramount biological importance, involved in the regulation of a significant number of cellular functions through the cAMP-dependent intracellular signal transduction pathways. The aim of this “Frontiers in Pharmacology Research Topic” is to attract contributions that highlight emerging ideas in the cAMP field that: (i) describe its role in cellular function and homeostasis, (ii) present the current approaches to its pharmacological manipulation, (iii) clarify its central role in the development of more targeted therapeutic approaches towards a spectrum of cardiovascular, neurodegenerative and metabolic diseases.

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