According to World Health Organization, noncommunicable diseases (NCDs), are responsible for almost 70% of all deaths worldwide and makeup 7 of the world’s top 10 causes of death. In recent years, NCDs
have been considered a major public health problem and a significant burden on health care systems.
The consumption of food is considered one of the primary risk factors for NCDs and a healthier diet may contribute to disease prevention and management. Non-nutrient microconstituents, such as phytochemicals may not be essential for the body, but they can have great benefits for human health, particularly against NCDs. Several studies have revealed potential anti-inflammatory, antioxidant, anti-hyperglycemic, anti-hypertensive, and antilipidemic perspectives of non-nutrient microconstituents. The majority of these study outcomes are related to modulations of metabolic pathways implicated in NCDs.
Despite the large number of studies on the molecular pathways non-nutrient microconstituents exhibit their actions on NCDs, this research area remains underexplored, especially in terms of impacting plasma
metabolites, microRNA regulation, oral and gut microbiota. Therefore, advances in the above aspects should include:
1) exploring the role of non-nutrient microconstituents on the prevention and management of NCDs
2) identifying potential mediators and targets that mediate this activity role
3)suggesting possible cellular and molecular pathways underlying this action
4) identifying new potential biomarkers that contribute to disease prediction and management.
Therefore, the scope of this Research Topic is to provide new insights into the mechanisms by which non-nutrient microconstituents affect NCDs. We welcome original research articles as well as review articles and potential themes include, but are not limited to:
- Potential targets, mediators, cellular and molecular pathways regulated by non-nutrient microconstituents in NCDs
- Identification of potential new biomarkers related to NCDs and altered by the action of non-nutrient microconstituents
- Bioavailability of non-nutrient microconstituents and their metabolic fate
- Metabolomics, oral and gut microbiota, miRNA levels alterations related to non-nutrient microconstituents and NCDs
- Application of novel techniques in the identification of non-nutrient microconstituents that are implicated in NCDs
According to World Health Organization, noncommunicable diseases (NCDs), are responsible for almost 70% of all deaths worldwide and makeup 7 of the world’s top 10 causes of death. In recent years, NCDs
have been considered a major public health problem and a significant burden on health care systems.
The consumption of food is considered one of the primary risk factors for NCDs and a healthier diet may contribute to disease prevention and management. Non-nutrient microconstituents, such as phytochemicals may not be essential for the body, but they can have great benefits for human health, particularly against NCDs. Several studies have revealed potential anti-inflammatory, antioxidant, anti-hyperglycemic, anti-hypertensive, and antilipidemic perspectives of non-nutrient microconstituents. The majority of these study outcomes are related to modulations of metabolic pathways implicated in NCDs.
Despite the large number of studies on the molecular pathways non-nutrient microconstituents exhibit their actions on NCDs, this research area remains underexplored, especially in terms of impacting plasma
metabolites, microRNA regulation, oral and gut microbiota. Therefore, advances in the above aspects should include:
1) exploring the role of non-nutrient microconstituents on the prevention and management of NCDs
2) identifying potential mediators and targets that mediate this activity role
3)suggesting possible cellular and molecular pathways underlying this action
4) identifying new potential biomarkers that contribute to disease prediction and management.
Therefore, the scope of this Research Topic is to provide new insights into the mechanisms by which non-nutrient microconstituents affect NCDs. We welcome original research articles as well as review articles and potential themes include, but are not limited to:
- Potential targets, mediators, cellular and molecular pathways regulated by non-nutrient microconstituents in NCDs
- Identification of potential new biomarkers related to NCDs and altered by the action of non-nutrient microconstituents
- Bioavailability of non-nutrient microconstituents and their metabolic fate
- Metabolomics, oral and gut microbiota, miRNA levels alterations related to non-nutrient microconstituents and NCDs
- Application of novel techniques in the identification of non-nutrient microconstituents that are implicated in NCDs
