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Even though advocated in all guidelines, individuals with Type 1 Diabetes face numerous barriers to attend regular physical activity on a daily basis. In the 21st century CGM systems, hybrid closed-loops/closed-loop systems have become widely available besides the regular pen therapy with bolus and basal ...

Even though advocated in all guidelines, individuals with Type 1 Diabetes face numerous barriers to attend regular physical activity on a daily basis. In the 21st century CGM systems, hybrid closed-loops/closed-loop systems have become widely available besides the regular pen therapy with bolus and basal insulin. However, blood glucose measurements are still performed by individuals with Type 1 Diabetes prior to and during exercise to confirm values given by the CGM. Rapid changes in blood glucose may not always be detected by CGMS fast enough following an insulin correction or ‘rescue carbohydrates’ around exercise which is why individuals with Type 1 Diabetes need to be vigilant prior to- and post-exercise to avoid dangerous dysglycemic episodes. An often-neglected topic is the physiological response besides the glucose metabolism to physical exercise in individuals with Type 1 Diabetes. It is yet unknown how regular exercise may affect the muscular physiology, cardiac adaptions and hormonal response in regular active individuals. Even though the insulin management plays a vital role in the management of Type 1 Diabetes, exercise induced responses in adrenaline, noradrenaline, dopamine and cortisol may affect the response to dietary carbohydrates and post-exercise glycemic management.

This special issue aims to outline exercise induced changes in the individual’s physiology via nutrition, exercise induced change in regulatory hormones in individuals with Type 1 Diabetes.

Both review and original research articles are welcomed.

Keywords: Type 1 Diabetes, Physical Activity, Exercise, CGM, Insulin, Glucose, Hyperglycemia, Hypoglycemia, Heart Rate Variability, Cardiac Response, Quality of Life, Time in range


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