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About this Research Topic

Manuscript Submission Deadline 21 December 2022
Manuscript Extension Submission Deadline 20 January 2023

Cardiovascular diseases are the leading cause of death accounting for about 30% of deaths worldwide. Among these diseases, the incidence and prevalence of cardiac arrhythmias and other pathologies related to cardiac electrophysiology are reaching epidemic proportions. Despite the high incidence and intensive research and clinical efforts, the ability to treat such pathologies remains a huge healthcare challenge.

Recognizing the future leaders in cardiac electrophysiology is fundamental to addressing these challenges and safeguarding tomorrow's driving force in innovation and clinical translation. This Research Topic will showcase the high-quality work of up-and-coming researchers in the early stages of their careers (specifically within 10 years of their PhD or MD completion), who will drive this field forward in the years to come.

The Topic will cover themes across the entire breadth of cardiac electrophysiology, ranging from molecular and cellular electrophysiology to experiment and methodology and patient-related clinical and translational cardiac electrophysiology. It welcomes original papers on the foundations of cardiac electrophysiology, its modulation (genetic, pharmacologic, neuronal), as well as on the origin and mechanism of arrhythmias.

We welcome papers covering, but not limited to, the following areas:
- supraventricular/ventricular arrhythmias
- mechanisms of cardiac arrhythmias:
- genetics
- molecular mechanisms
- comorbidities/aging
- autonomic modulation of cardiac electrophysiology
- cellular cardiac electrophysiology
- clinical electrophysiology
- in silico modelling in cardiac electrophysiology
- excitation-contraction-coupling and cardiac calcium handling
- tissue and cellular (micro-)architecture and arrhythmogenesis
- methods in cardiac electrophysiology (electrograms, ECG, optical mapping)
- biomedical engineering in cardiac electrophysiology
- pacing, defibrillation and ablation
- novel diagnostic tools for arrhythmia
- signal processing and machine learning approaches

Cardiac electrophysiology is one of the fields with the strongest scientific and technical developments over the last decades. Multidisciplinary research in particular has been very successful in solving complex cardiology problems. New developments, such as automation and robotics, should help eliminate the factor of human error in future procedures.

Hence, this topic will also cover future challenges of integrating multidisciplinary ideas and advanced technologies into the management of cardiac arrhythmias, such as:

- artificial intelligence
- computer modelling
- advanced imaging techniques
- procedure guidance systems
- robotic catheters
- optogenetics
- gene therapy
- radiation therapy

All early-career researchers will be suggested by the editorial office and established Editors within our board in recognition of their influence on the future directions in their respective fields. Self-nominations are also welcomed and assessed by the editorial team, so please inform the Editorial Office at physiology@frontiersin.org if you would like to be considered for participation in this collection. While future innovations in cardiac electrophysiology are yet to be discovered, this Research Topic will give the community a hint at whom to follow.

This Research Topic is part of the Rising Stars in Physiology Series. Other titles in the series are: 

Rising Stars in Vascular Physiology: 2022
Rising Stars in Exercise Physiology
Rising Stars in Environmental, Aviation and Space Physiology: 2022
Rising Stars in Avian Physiology: 2022
Rising Stars in Invertebrate Physiology: 2022
Rising Stars in Metabolic Physiology: 2022
Rising Stars in Physio-logging: 2022
Rising Stars in Craniofacial Biology and Dental Research: 2022
Rising Stars in Gastrointestinal Sciences: 2022
Rising Stars in Red Blood Cell Physiology: 2022
Rising Stars in Respiratory Physiology: 2022
Rising Stars in Integrative Physiology: 2022
Rising Stars in Striated Muscle Physiology: 2022
Rising Stars in Renal and Epithelial Physiology: 2022
Rising Stars in Developmental Physiology: 2022
Rising Stars in Redox Physiology: 2022
Rising Stars in Chronobiology: 2022
Rising Stars in Aquatic Physiology: 2022

Keywords: cardiac electrophysiology, rising stars, early-career


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Cardiovascular diseases are the leading cause of death accounting for about 30% of deaths worldwide. Among these diseases, the incidence and prevalence of cardiac arrhythmias and other pathologies related to cardiac electrophysiology are reaching epidemic proportions. Despite the high incidence and intensive research and clinical efforts, the ability to treat such pathologies remains a huge healthcare challenge.

Recognizing the future leaders in cardiac electrophysiology is fundamental to addressing these challenges and safeguarding tomorrow's driving force in innovation and clinical translation. This Research Topic will showcase the high-quality work of up-and-coming researchers in the early stages of their careers (specifically within 10 years of their PhD or MD completion), who will drive this field forward in the years to come.

The Topic will cover themes across the entire breadth of cardiac electrophysiology, ranging from molecular and cellular electrophysiology to experiment and methodology and patient-related clinical and translational cardiac electrophysiology. It welcomes original papers on the foundations of cardiac electrophysiology, its modulation (genetic, pharmacologic, neuronal), as well as on the origin and mechanism of arrhythmias.

We welcome papers covering, but not limited to, the following areas:
- supraventricular/ventricular arrhythmias
- mechanisms of cardiac arrhythmias:
- genetics
- molecular mechanisms
- comorbidities/aging
- autonomic modulation of cardiac electrophysiology
- cellular cardiac electrophysiology
- clinical electrophysiology
- in silico modelling in cardiac electrophysiology
- excitation-contraction-coupling and cardiac calcium handling
- tissue and cellular (micro-)architecture and arrhythmogenesis
- methods in cardiac electrophysiology (electrograms, ECG, optical mapping)
- biomedical engineering in cardiac electrophysiology
- pacing, defibrillation and ablation
- novel diagnostic tools for arrhythmia
- signal processing and machine learning approaches

Cardiac electrophysiology is one of the fields with the strongest scientific and technical developments over the last decades. Multidisciplinary research in particular has been very successful in solving complex cardiology problems. New developments, such as automation and robotics, should help eliminate the factor of human error in future procedures.

Hence, this topic will also cover future challenges of integrating multidisciplinary ideas and advanced technologies into the management of cardiac arrhythmias, such as:

- artificial intelligence
- computer modelling
- advanced imaging techniques
- procedure guidance systems
- robotic catheters
- optogenetics
- gene therapy
- radiation therapy

All early-career researchers will be suggested by the editorial office and established Editors within our board in recognition of their influence on the future directions in their respective fields. Self-nominations are also welcomed and assessed by the editorial team, so please inform the Editorial Office at physiology@frontiersin.org if you would like to be considered for participation in this collection. While future innovations in cardiac electrophysiology are yet to be discovered, this Research Topic will give the community a hint at whom to follow.

This Research Topic is part of the Rising Stars in Physiology Series. Other titles in the series are: 

Rising Stars in Vascular Physiology: 2022
Rising Stars in Exercise Physiology
Rising Stars in Environmental, Aviation and Space Physiology: 2022
Rising Stars in Avian Physiology: 2022
Rising Stars in Invertebrate Physiology: 2022
Rising Stars in Metabolic Physiology: 2022
Rising Stars in Physio-logging: 2022
Rising Stars in Craniofacial Biology and Dental Research: 2022
Rising Stars in Gastrointestinal Sciences: 2022
Rising Stars in Red Blood Cell Physiology: 2022
Rising Stars in Respiratory Physiology: 2022
Rising Stars in Integrative Physiology: 2022
Rising Stars in Striated Muscle Physiology: 2022
Rising Stars in Renal and Epithelial Physiology: 2022
Rising Stars in Developmental Physiology: 2022
Rising Stars in Redox Physiology: 2022
Rising Stars in Chronobiology: 2022
Rising Stars in Aquatic Physiology: 2022

Keywords: cardiac electrophysiology, rising stars, early-career


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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