About this Research Topic
Psychedelic compounds use has a rich and complicated history spanning through ancient cultures, modern medical use, cultural movements and national and international politics. With the latest resurgence of use of these compounds in mental health and medical conditions, we are just scratching the surface of understanding the mechanisms that underlie these drugs' effects and their ways of action in the single body and in society as a whole.
The goal of this Research Topic is to examine the neurobiological and psychological mechanisms underlying psychedelic compounds effects in healthy clinical populations, shedding light on new paradigms, approaches and data from basic research, as well as clinical and intervention studies in neuroscience, biology, social medicine, philosophy and psychology. The aim of this Research Topic is to highlight new interdisciplinary research on psychedelic compounds and understand their mechanisms of action and their effects. Topics may include:
• Basic science research about the neural basis of psychedelic compounds effects (both in animal models and in humans)
• Research on either psilocybin, ayahuasca, ketamine, salvia, LSD, MDMA, ibogaine, and 5HT2A agonists (or antagonists).
• Studies about interactions between said compounds and other neurotransmitters, neurohormones and other substances.
• Intervention studies (pharmacological and assisted psychotherapy) regarding the effects of psychedelic compounds in mental health and other medical conditions (either RCT or other types of research).
• Reviews, meta-analyses, methodology papers, and original research on the effects of psychedelics.
The goal of this Research Topic is to examine the neurobiological and psychological mechanisms underlying psychedelic compounds effects in healthy clinical populations, shedding light on new paradigms, approaches and data from basic research, as well as clinical and intervention studies in neuroscience, biology, social medicine, philosophy and psychology. The aim of this Research Topic is to highlight new interdisciplinary research on psychedelic compounds and understand their mechanisms of action and their effects. Topics may include:
• Basic science research about the neural basis of psychedelic compounds effects (both in animal models and in humans)
• Research on either psilocybin, ayahuasca, ketamine, salvia, LSD, MDMA, ibogaine, and 5HT2A agonists (or antagonists).
• Studies about interactions between said compounds and other neurotransmitters, neurohormones and other substances.
• Intervention studies (pharmacological and assisted psychotherapy) regarding the effects of psychedelic compounds in mental health and other medical conditions (either RCT or other types of research).
• Reviews, meta-analyses, methodology papers, and original research on the effects of psychedelics.
Keywords: neural plasticity, psychedelics, synaptogenesis, 5HT-2A, imaging, fMRI, MEG, EEG, depression, OCD, eating disorders, PTSD, LSD, DMT, ketamine, ibogaine, MDMA
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