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High-density farming, intense human activities, and global climate change can cause environmental deterioration, imbalances in the microecosystem and blooms of pathogens. As a result, bacterial pathogens rapidly emerged and threatened the quality and production of aquaculture worldwide. The overuse or misuse ...

High-density farming, intense human activities, and global climate change can cause environmental deterioration, imbalances in the microecosystem and blooms of pathogens. As a result, bacterial pathogens rapidly emerged and threatened the quality and production of aquaculture worldwide. The overuse or misuse of drugs, including antibiotics during culture should lead to drug-resistant and even drug-ineffective, bringing about huge economic loss and food safety-related issues. Environmental changes, including antibiotic residue, high nutritional load, biocides and heavy metals pollution, and global warming, can adjust the enzyme activity, affect plasmid replication, change phage activity and prevent immune systems, thus mediating the prevalence and transmission of microbial virulence and antimicrobial resistance (AMR).

To achieve the goal of healthier and more nutritious aquaculture which is launched by Food and Agriculture Organization of the United Nations (FAO), the “Green and Healthy Aquaculture" initiative is implemented. The specific Research Topic dedicates to early disease detection, monitoring of pathogen resistance, determining suitable local antimicrobial profiles, providing guidance for scientific medication, and vigorously promoting immune and ecological disease prevention and control.

The focus of this Research Topic is on the prevalence and transmission of microbial virulence and AMR, the key influencing mechanisms of environmental change on the virulence and AMR, and the control of microbial virulence and AMR based on environmental regulation. We look forward to publishing your latest research results in the form of original articles and reviews. The manuscript scope includes (but is not limited to) the following contents:

• The prevalence and transmission of microbial virulence and AMR in aquacultural system
• The interaction mechanism between environment factor and microbial virulence & AMR
• The evolution mechanisms of pathogenicity and drug resistance in aquatic pathogens in response to environmental stress
• The control of microbial virulence and AMR by environment regulation

Keywords: aquaculture, aquatic microorganism, microbial virulence, AMR, environment change, prevalence and transmission, evolution mechanisms, environment regulation


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