Advances in Brain Disorders: from Mechanisms to Therapeutic Targets

53.3K

views

153

authors

21

articles

Advances in Brain Disorders: from Mechanisms to Therapeutic Targets

53.3K

views

153

authors

21

articles

Editorial

28 November 2023

Editorial: Advances in brain disorders: from mechanisms to therapeutic targets

Federica Bono

,

Giulia Abate

,

Sara Anna Bonini

,

Maria Josè Sisalli

and

Arianna Bellucci

730 views

0 citations

Editors

5

Arianna Bellucci

University of Brescia

Federica Bono

University of Brescia

Sara Anna Bonini

University of Brescia

Maria Jose Sisalli

University of Naples Federico II

GIULIA ABATE

University of Brescia

Impact

Fetching...

About

This Research Topic is in Partnership with the 2022 "Italian Society for Neuroscience National Meeting of PhD Students in Neuroscience conference."

Neurological disorders such as Alzheimer’s disease and other dementias, Parkinson’s disease, multiple sclerosis, traumatic brain injury, epilepsy, migraine, depression, stroke, and neurodevelopmental disorders such as schizophrenia or autism spectrum disorders account for one-third of the burden of all diseases in the wealthy part of the world. These represent one of the biggest challenges for National Health Systems in terms of economic costs. For instance, it has been estimated that in 2004, 127 million European citizens were living with a brain disorder, for a total annual cost of 385 billion euros. Unfortunately, for most brain disorders, we are still missing effective therapies because since many years we are facing the unmet need of defining the key molecular underpinnings of disease. However, it is clear that the integration of data deriving from basic and clinical research studies is pivotal for a better comprehension of the biological basis of brain disorders and for the identification of novel therapeutic targets to develop innovative pharmacological approaches.

This Research Topic aims at integrating basic and clinical research reports, reviews or viewpoints presenting novel mechanisms involved in acute and chronic brain disorders, highlighting the identification of innovative therapeutic targets or discussing gaps and controversies related to experimental models or therapeutic management of brain disorders.

This Research Topic will collect full research reports, review articles, meta-analyses or viewpoints. Studies examining all levels of inquiry, from basic to applied or clinical science and also methodological papers using a wide range of techniques and model systems, are welcome.

Download ebook

PDF

EPUB

Share

Editors

Arianna Bellucci

University of Brescia

Federica Bono

University of Brescia

Sara Anna Bonini

University of Brescia

Maria Jose Sisalli

University of Naples Federico II

GIULIA ABATE

University of Brescia

Impact

53,304 Total views

39,679 Article views

12,555 Article downloads

1,070 Topic views

Published In

Frontiers in Molecular Neuroscience

Brain Disease Mechanisms

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic