Stroke is the third leading cause of death, and ischemic stroke is the most common subtype, accounting for more than 80% of all strokes. Currently, the main therapy for ischemic stroke is to restore the cerebral blood flow as soon as possible to prevent the enlargement of the infarct core. Revascularization by intravenous thrombolysis or endovascular thrombectomy has been demonstrated to be the most effective therapy for the treatment of ischemic stroke worldwide, however, only 10% or fewer patients can receive these treatments.
Neuroprotection has been considered as an adjunctive approach to reperfusion therapy. The recent success of endovascular therapy for ischemic stroke provides new opportunities for the development of neuroprotection. Currently, there is an urgent need for novel, easy-to-use neuroprotective strategies that are available for stroke; any strategy that can extend the therapeutic time window before endovascular therapy or reduce reperfusion injury after that would have great clinical significance.
Investigations of advanced neuroimaging techniques and the physiopathological mechanisms will greatly promote the translation of neuroprotective therapy. To address the limitations of current therapies and to identify and develop novel neuroprotective strategies, further research into physiopathological mechanisms of acute ischemic stroke and neuroimaging methods is urgently needed.
Token together, we call for manuscripts in the field of neuroprotective strategies in acute stroke and its related conditions. The topic editors welcome both pre-clinical and clinical stroke research and any type of manuscript including Original Research, Review, Brief Research Report, and Mini Review. Please note that Case Reports are not welcome. The themes include but are not limited to the followings:
• Physiopathological mechanisms of acute stroke.
• Reperfusion therapies and neuroimaging techniques for acute ischemic stroke.
• Innovative research in neuroprotection, especially non-pharmaceutical strategies, such as oxygen, hypothermia, and ischemic pre-, per-, or post-conditioning.
Stroke is the third leading cause of death, and ischemic stroke is the most common subtype, accounting for more than 80% of all strokes. Currently, the main therapy for ischemic stroke is to restore the cerebral blood flow as soon as possible to prevent the enlargement of the infarct core. Revascularization by intravenous thrombolysis or endovascular thrombectomy has been demonstrated to be the most effective therapy for the treatment of ischemic stroke worldwide, however, only 10% or fewer patients can receive these treatments.
Neuroprotection has been considered as an adjunctive approach to reperfusion therapy. The recent success of endovascular therapy for ischemic stroke provides new opportunities for the development of neuroprotection. Currently, there is an urgent need for novel, easy-to-use neuroprotective strategies that are available for stroke; any strategy that can extend the therapeutic time window before endovascular therapy or reduce reperfusion injury after that would have great clinical significance.
Investigations of advanced neuroimaging techniques and the physiopathological mechanisms will greatly promote the translation of neuroprotective therapy. To address the limitations of current therapies and to identify and develop novel neuroprotective strategies, further research into physiopathological mechanisms of acute ischemic stroke and neuroimaging methods is urgently needed.
Token together, we call for manuscripts in the field of neuroprotective strategies in acute stroke and its related conditions. The topic editors welcome both pre-clinical and clinical stroke research and any type of manuscript including Original Research, Review, Brief Research Report, and Mini Review. Please note that Case Reports are not welcome. The themes include but are not limited to the followings:
• Physiopathological mechanisms of acute stroke.
• Reperfusion therapies and neuroimaging techniques for acute ischemic stroke.
• Innovative research in neuroprotection, especially non-pharmaceutical strategies, such as oxygen, hypothermia, and ischemic pre-, per-, or post-conditioning.
