Research Topic

Mathematical and Computational Models of Biochemical Dynamics related to Memory Formation and Impairment

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During the last several decades, the biochemical findings on synaptic plasticity and memory in neurons have led to new insights into memory formation and impairment. It is important, however, to underpin these new discoveries with novel mathematical models rooted, for example, in biophysics and pathway ...

During the last several decades, the biochemical findings on synaptic plasticity and memory in neurons have led to new insights into memory formation and impairment. It is important, however, to underpin these new discoveries with novel mathematical models rooted, for example, in biophysics and pathway modelling to help us understand the complex dynamics associated with the related biochemical processes. Therefore, this is a call to biological scientists, mathematicians, physicists, and engineers who develop models in these areas to contribute their recent work for publication in this Research Topic.

We encourage papers on rigorous theoretical treatments that can provide frameworks to understand experimental results. Research based on interdisciplinary interactions and associated insightful theoretical work is also encouraged.

Potential topics may have a broad scope: mathematical models related to specific aspects of memory and its impairment; models related to long term potentiation; protein-protein interaction networks related to presynaptic and postsynaptic processes; biophysics of neuronal membrane channels and receptors; stochastic dynamics of single biomolecules and pathways; and various other issues related to synaptic processes.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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