About this Research Topic
Metabolic syndrome is a dangerous combination of cardiovascular risk factors that correlate with each other and can increase cardio and cerebrovascular events. The incidence of metabolic syndrome often parallels that of obesity and type 2 diabetes. It is widespread; in the United States, more than 40% of people over the age of 50 have metabolic syndrome. The diagnosis of metabolic syndrome is based on the coexistence of at least three risk factors including waist circumference greater than 102 cm in men or 88 cm in women, systolic blood pressure greater than 130 mmHg and diastolic greater than 85 mmHg, HDL cholesterol less than 40 mg/dl in men or 50 mg/dl in women, triglyceridemia higher than 150 mg/dl and finally fasting glycaemia higher than 110 mg/dl.
The causes are to be found in a combination of lifestyle habits (diet and poor physical activity) and family predisposition (genetics). These causes lead to the accumulation of abdominal fat, which in turn plays a decisive role in favoring the combination of the various risk factors. Among these, insulin resistance is fundamental in the onset not only of hyperglycemia and diabetes, but also of dyslipidemia and hypertension. Metabolic syndrome does not manifest itself with specific symptoms, which is why attention should be paid to risk factors.
With this in mind, we welcome researchers investigating this contemporary theme. This Research Topic welcomes original research articles, perspectives, and review articles.
The causes are to be found in a combination of lifestyle habits (diet and poor physical activity) and family predisposition (genetics). These causes lead to the accumulation of abdominal fat, which in turn plays a decisive role in favoring the combination of the various risk factors. Among these, insulin resistance is fundamental in the onset not only of hyperglycemia and diabetes, but also of dyslipidemia and hypertension. Metabolic syndrome does not manifest itself with specific symptoms, which is why attention should be paid to risk factors.
With this in mind, we welcome researchers investigating this contemporary theme. This Research Topic welcomes original research articles, perspectives, and review articles.
Keywords: metabolic syndrome, cardiovascular disease, cellular mechanisms
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
