About this Research Topic

Abstract Submission Deadline 31 October 2022
Manuscript Submission Deadline 31 January 2023

Sinus venosus atrial septal defect (SV-ASD) is a rare type of ASD representing 5-10% of all ASDs. Unlike type I and type II ASDs which are caused by incomplete fusion of septum primum and secundum, sinus venosus ASDs are caused by a deficiency of the common wall between the superior or more rarely the inferior vena cava and the right-sided pulmonary veins. Up to 90% of SV-ASDs are associated with partial anomalous pulmonary venous drainage (PAPVD). SV-ASDs are difficult to diagnose with transthoraccardiac ultrasound and often transesophageal echocardiogram or cardiac CT are necessary to obtain complete diagnosis. Currently, cardiac surgery is the most used treatment option yet interventional treatment is gaining interest. Although surgery is highly successful there is a risk of stenosis of the superior vena cava or pulmonary veins, residual shunting, sinoatrial node dysfunction and arrhythmias, underscoring the need for even more improvement in diagnosis and treatment of SV-ASD.

We aim to optimize understanding of the cause of SV-ASD and its embryology. In addition, improved and novel imaging techniques could lead to early diagnosis and to advancements in treatment outcomes. Sharing experiences on further improved and less invasive correction can enhance outcome even further. Finally, an update on the origin of arrythmias seen in patients with SV-ASD could improve anti-arrhythmic treatment including drugs and catheter ablation.

This Research Topic is open to articles presenting novel evidence on the causes of, diagnosis and treatment of SV-ASD, including
• Embryology and anatomy of SV-ASD
• Fetal imaging and diagnosis of SV-ASD
• Imaging of SV-ASD such as cardiac ultrasound, CT scan and MRI
• Surgical correction of SV-ASD
• Interventional treatment of SV-ASD
• Anti-arrhythmic drugs and ablation options to treat SV-ASD related arrhythmias.

This call is open to case reports, review articles and research articles.

Keywords: Sinus Venosus Atrial Septal Defects, Embryology of atrial development, interventional treatment of sinus venosus ASD, Pediatric Cardiology, Surgical correction of sinus venosus ASD


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Sinus venosus atrial septal defect (SV-ASD) is a rare type of ASD representing 5-10% of all ASDs. Unlike type I and type II ASDs which are caused by incomplete fusion of septum primum and secundum, sinus venosus ASDs are caused by a deficiency of the common wall between the superior or more rarely the inferior vena cava and the right-sided pulmonary veins. Up to 90% of SV-ASDs are associated with partial anomalous pulmonary venous drainage (PAPVD). SV-ASDs are difficult to diagnose with transthoraccardiac ultrasound and often transesophageal echocardiogram or cardiac CT are necessary to obtain complete diagnosis. Currently, cardiac surgery is the most used treatment option yet interventional treatment is gaining interest. Although surgery is highly successful there is a risk of stenosis of the superior vena cava or pulmonary veins, residual shunting, sinoatrial node dysfunction and arrhythmias, underscoring the need for even more improvement in diagnosis and treatment of SV-ASD.

We aim to optimize understanding of the cause of SV-ASD and its embryology. In addition, improved and novel imaging techniques could lead to early diagnosis and to advancements in treatment outcomes. Sharing experiences on further improved and less invasive correction can enhance outcome even further. Finally, an update on the origin of arrythmias seen in patients with SV-ASD could improve anti-arrhythmic treatment including drugs and catheter ablation.

This Research Topic is open to articles presenting novel evidence on the causes of, diagnosis and treatment of SV-ASD, including
• Embryology and anatomy of SV-ASD
• Fetal imaging and diagnosis of SV-ASD
• Imaging of SV-ASD such as cardiac ultrasound, CT scan and MRI
• Surgical correction of SV-ASD
• Interventional treatment of SV-ASD
• Anti-arrhythmic drugs and ablation options to treat SV-ASD related arrhythmias.

This call is open to case reports, review articles and research articles.

Keywords: Sinus Venosus Atrial Septal Defects, Embryology of atrial development, interventional treatment of sinus venosus ASD, Pediatric Cardiology, Surgical correction of sinus venosus ASD


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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