About this Research Topic
Environmental pollution, including but not limited to chemical exposure, air pollution (Particulate Matter and Ozone), heavy metals, Radiation, and others, has become one of the most serious health threats to humans. Epidemiological studies have shown that environmental pollution was associated with various diseases, such as respiratory and cardiovascular diseases and cancer.
Epigenetics is developing rapidly, which links environmental exposures and organisms. Disruptions in the epigenome lead to gene expression alteration and affect genetic signatures. Epigenetic changes, including chromatin modifications, DNA and RNA methylations, and changes in non-coding RNAs, play pivotal roles in the aetiology of multiple diseases. However, more evidence is still required. Due to the advantages of high-throughput sequencing, epigenomics-wide identification will strengthen the tie between environmental exposure and disease processes and reveal how environmental exposure affects human health through epigenetic changes.
The aim of the current Research Topic is to cover promising and novel research trends in the epigenetic regulations in diseases affected by environmental pollution. Areas to be covered in this Research Topic may include, but are not limited to:
• Epigenetics modification profile of SARS-CoV-2
• Relationship between epigenetics and environmental exposure-induced immune escape
• Investigation of omics, such as single-cell assays for transposase-accessible chromatin (scATAC-seq), Methylated RNA immunoprecipitation sequencing (meRIP-seq), under a variety of environmental exposures
• Relationship between epigenetics and diseases
• Relationship between epigenetics and Pathogenic Microbes, such as bacteria and fungal
Epigenetics is developing rapidly, which links environmental exposures and organisms. Disruptions in the epigenome lead to gene expression alteration and affect genetic signatures. Epigenetic changes, including chromatin modifications, DNA and RNA methylations, and changes in non-coding RNAs, play pivotal roles in the aetiology of multiple diseases. However, more evidence is still required. Due to the advantages of high-throughput sequencing, epigenomics-wide identification will strengthen the tie between environmental exposure and disease processes and reveal how environmental exposure affects human health through epigenetic changes.
The aim of the current Research Topic is to cover promising and novel research trends in the epigenetic regulations in diseases affected by environmental pollution. Areas to be covered in this Research Topic may include, but are not limited to:
• Epigenetics modification profile of SARS-CoV-2
• Relationship between epigenetics and environmental exposure-induced immune escape
• Investigation of omics, such as single-cell assays for transposase-accessible chromatin (scATAC-seq), Methylated RNA immunoprecipitation sequencing (meRIP-seq), under a variety of environmental exposures
• Relationship between epigenetics and diseases
• Relationship between epigenetics and Pathogenic Microbes, such as bacteria and fungal
Keywords: Epigenetics, environmental pollution, human health, high-throughput sequencing, omics, pathogenic microbes
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