About this Research Topic
In the quest for developing reproducible procedures for monitoring the distribution and migration of specific cell populations in living organisms, the use of nanoparticles labelling strategies can be a key element for success. Nanoparticle tracking can be obtained by diverse detection approaches (optical, photo-acoustic, magnetic, PET, and SPECT) each one characterized by specific and complementary characteristics (spatial resolution, sensitivity, penetration depth, signal stability, etc.). Such versatility can greatly benefit to oncological research (e.g., identification of metastatic potential, monitoring of metastasis formation or therapeutic efficacy) and cell-therapies development and efficacy assessment including regenerative medicine approaches.
This Research Topic aims at disseminating to a large and interdisciplinary community the state-of-the-art on nanoparticles based cell tracking, highlighting its possibilities, limitations and clarifying the aptness of different techniques for specific research problems. The Topic is open to contributions describing novel methods (from the nanotechnology and/or detection standpoint), interactions among nanoparticles and host organisms (toxicity, retention time, metabolism change upon labelling), in vitro models (tissue scaffolds, three dimensional cultures,…) in silico modelling and image tracking analysis.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.