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Single Photon Emission Computed Tomography (SPECT) is a nuclear medicine imaging technique that provides direct 3-dimentional functional and molecular information in vivo, with the use of radioactive tracers emitting gamma rays. This provides information that assists in the diagnosis, treatment planning and ...

Single Photon Emission Computed Tomography (SPECT) is a nuclear medicine imaging technique that provides direct 3-dimentional functional and molecular information in vivo, with the use of radioactive tracers emitting gamma rays. This provides information that assists in the diagnosis, treatment planning and monitoring of a wide spectrum of applications such as oncology, cardiology, neurology, pulmonology and nephrology.

Before the scan, a radiolabeled tracer is administered to the patients, most commonly via intravenous injection. The emitted gamma rays are then detected by the gamma cameras at different angles. The projection information is then reconstructed and displayed as a 3-D image.

There is a wide spectrum of radioactive tracers isotopes available for clinical and preclinical SPECT, with the most commonly used being Technetium-99m (99m Tc).

This Research Topic aims to collect the latest advances in SPECT, covering instrumentation, reconstruction, artificial intelligence, tracer development and applications.

Keywords: Single Photon Emission Computed Tomography, SPECT, diagnostics


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