Fish and other aquatic animals have attracted more neuroscience-relevant research in recent years. Compared to rodents or mammalian systems, fish is easier to handle, less costly, and allows researchers to do some quick tests. Many exciting research and review papers have been reported showing remarkable similarities between fish and high vertebrates regarding neurotransmitters, neural circuits, behavior control mechanisms, etc. Some model fish like zebrafish and medaka attract more attention for researchers since many genetic mutants have already been established, and molecular manipulation tools are also available. My lab and other labs have developed several interesting methods and experimental setups over the last five years that can be used to conduct various behavioral assays such as color preference, circadian rhythm, T-maze, passive avoidance, predator avoidance, 3D locomotion, mirror biting, and shoaling. These behavioral assay batteries enable to perform Phenomic assessments to be performed to analyze the potential effects of pollutants or substances at toxicological and pharmacological levels. In addition, those established tools also can be used to evaluate the potential behavioral abnormality in mutant fish lines created by transgenesis or genome editing. In this Research Topic of "Frontiers in Molecular Neuroscience", we invite scientists worldwide to submit their original works or review articles to share their updated research breakthroughs and important findings.
Some research topics of interest that cover the following issues (but are not only limited) will be welcome:
• New behavioral assay method/setup and application: Innovated method or setup that is able to study fish behavior.
• Locomotion tracking tools and application: new deep learning- or machine vision-based tools that can conduct locomotion tracking in fish
• Physiological or molecular tools and application: a new approach using multiple endpoints like oxidative stress, neurohormone, neurotransmitter, and gene expression profiling to evaluate neurotoxicity
• Genome editing and transgenesis tools: new genetic mutants and transgenic lines display behavioral abnormalities that can help us to understand better gene function associated with neurobehavioral control
Fish and other aquatic animals have attracted more neuroscience-relevant research in recent years. Compared to rodents or mammalian systems, fish is easier to handle, less costly, and allows researchers to do some quick tests. Many exciting research and review papers have been reported showing remarkable similarities between fish and high vertebrates regarding neurotransmitters, neural circuits, behavior control mechanisms, etc. Some model fish like zebrafish and medaka attract more attention for researchers since many genetic mutants have already been established, and molecular manipulation tools are also available. My lab and other labs have developed several interesting methods and experimental setups over the last five years that can be used to conduct various behavioral assays such as color preference, circadian rhythm, T-maze, passive avoidance, predator avoidance, 3D locomotion, mirror biting, and shoaling. These behavioral assay batteries enable to perform Phenomic assessments to be performed to analyze the potential effects of pollutants or substances at toxicological and pharmacological levels. In addition, those established tools also can be used to evaluate the potential behavioral abnormality in mutant fish lines created by transgenesis or genome editing. In this Research Topic of "Frontiers in Molecular Neuroscience", we invite scientists worldwide to submit their original works or review articles to share their updated research breakthroughs and important findings.
Some research topics of interest that cover the following issues (but are not only limited) will be welcome:
• New behavioral assay method/setup and application: Innovated method or setup that is able to study fish behavior.
• Locomotion tracking tools and application: new deep learning- or machine vision-based tools that can conduct locomotion tracking in fish
• Physiological or molecular tools and application: a new approach using multiple endpoints like oxidative stress, neurohormone, neurotransmitter, and gene expression profiling to evaluate neurotoxicity
• Genome editing and transgenesis tools: new genetic mutants and transgenic lines display behavioral abnormalities that can help us to understand better gene function associated with neurobehavioral control
