About this Research Topic
World Digestive Health Day takes place on the 29th of May, presenting a unique opportunity to focus on gut health. We wish to recognize this important day by drawing attention to the interaction between Neurodegenerative Disease and Gut Microbiota. Neurodegenerative diseases have traditionally been associated with the Central Nervous System. However, recent research has placed greater emphasis on the peripheral system due to the considerable impacts gut microbiota has on neurological processes such as behavior regulation and cognition. Additionally, gut microbiome is associated with the progression of many neurodegenerative disorders including Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis.
The exact nature of the relationship between the gut and neurodegenerative disease is yet to be determined. Gut microbiota is essential to maintaining regular functioning of microglia, which are integral in preventing neurodevelopmental divergence. However, it is also known that the gut microbiome is sensitive to external factors such as diet, sleep, circadian rhythm, and exercise that all play a role in gut health. Disturbance to gut microbiome and dysbiosis could be part of the etiology of neurodegenerative disorders. A broader comprehension of this bidirectional relationship could help advance current treatments and could ultimately help to prevent the progression of neurodegenerative disease.
Recent advances have contributed to our understanding of the involvement of gut microbiota in neurodegeneration, although there is still much to be understood. This Research Topic will be used as a platform to shine a light on the latest neurological research that investigates the bidirectional relationship between the gut and neurodegeneration.
In the spirit of forming a united front, Frontiers is launching a new article collection to coincide with World Digestive Health Day. This occasion not only offers an opportunity to acknowledge the current discoveries in the field, but also to consider future directions for the research.
Topics may include but are not limited to:
- Delineation of the gut microbiota and brain pathway
- Identifying and corroborating factors like sleep and obesity in dysbiosis
- Gut microbiome health and its impact on the regulation of normal and abnormal neurocognitive aging
- The influence of gut microbiota on the progression and etiology of neurodegenerative disease
- Gut microbiome health as a preventative measure against neurodegeneration
- Investigation into advancing current treatments through the manipulation of the gut microbiome
The exact nature of the relationship between the gut and neurodegenerative disease is yet to be determined. Gut microbiota is essential to maintaining regular functioning of microglia, which are integral in preventing neurodevelopmental divergence. However, it is also known that the gut microbiome is sensitive to external factors such as diet, sleep, circadian rhythm, and exercise that all play a role in gut health. Disturbance to gut microbiome and dysbiosis could be part of the etiology of neurodegenerative disorders. A broader comprehension of this bidirectional relationship could help advance current treatments and could ultimately help to prevent the progression of neurodegenerative disease.
Recent advances have contributed to our understanding of the involvement of gut microbiota in neurodegeneration, although there is still much to be understood. This Research Topic will be used as a platform to shine a light on the latest neurological research that investigates the bidirectional relationship between the gut and neurodegeneration.
In the spirit of forming a united front, Frontiers is launching a new article collection to coincide with World Digestive Health Day. This occasion not only offers an opportunity to acknowledge the current discoveries in the field, but also to consider future directions for the research.
Topics may include but are not limited to:
- Delineation of the gut microbiota and brain pathway
- Identifying and corroborating factors like sleep and obesity in dysbiosis
- Gut microbiome health and its impact on the regulation of normal and abnormal neurocognitive aging
- The influence of gut microbiota on the progression and etiology of neurodegenerative disease
- Gut microbiome health as a preventative measure against neurodegeneration
- Investigation into advancing current treatments through the manipulation of the gut microbiome
Keywords: Digestive Health, Neurodegeneration, Gut Micrbiota
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
