About this Research Topic

Abstract Submission Deadline 10 October 2022
Manuscript Submission Deadline 10 December 2022

Recent advances in the properties exhibited by light sources and luminescent materials have played a vital role in the development of several biophotonic applications, including spectrally, spatiotemporally resolved, and non-invasive investigations. These advances have also allowed precise and minimally invasive surgical procedures which utilise optical control or appropriate integration with microscopy systems/sensing devises. As a significant number of light-emitting molecules exist in our natural world, particularly in the human body, advanced light sources emitting a range of optical wavelengths have, therefore, been developed to explore various mechanisms in biology, as well as the early detection of a wide array of diseases. Typically, solid-state lasers emitting wavelengths located within the biological optical window have been widely used in imaging and sensing studies. In clinic, miniaturized and user-friendly light sources such as fibre lasers and semiconductor lasers have become a fantastic tool for physicians in both diagnosis and treatment. In recent years, quantum light sources have been developed for metrology, computing, and microscopy imaging, paving a novel route to overcome the limitations exhibited by optical physics. On the other hand, advanced luminescent materials exhibiting the advantages of low-cytotoxicity, biocompatibility, facile surface modification, etc., can be utilized as probes or tracers in high-sensitivity imaging. Furthermore, they have also been applied to bio-sensing systems for determining pH, temperature, gas molecules, inorganic ions, reactive oxygen species, hazardous chemicals, etc., and are of particular significance in biomedical and environmental applications.

The goal of this Research Topic is to collate recent research findings with respect to light sources and luminescent materials for biomedical applications, thereby providing an overview of state-of-the art research in the field. This collection will cover the development of novel light sources for use in both microscopy and spectroscopy. In addition, this collection will provide a platform to gain an enhanced understanding of various luminescent materials and how to utilize them in sensing applications, alongside the promotion of novel research ideas for light-matter interactions in biomedical specimens.

We welcome the submission of Reviews, Mini-Reviews, Perspectives, and Original Research. Topics of interest include, but are not limited to, the following fields:
- The utilization of novel lasers, LEDs, and other light sources for biomedical applications;
- Light sources and luminescent materials seeking to enhance the performance, efficiency, and the wavelength ranges for specific bio-sensing and imaging applications;
- Biocompatible and degradable optical emitters;
- Research pertaining to underlying material research and photophysical mechanisms in life science applications;
- Luminescent Biosensors.

Keywords: olid-state Laser, Semiconductor Laser, Gas Laser, Fiber Laser, Quantum Light Source, Phosphor, Scintillator, Light-emitting Diode, Upconversion Nanoparticle


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent advances in the properties exhibited by light sources and luminescent materials have played a vital role in the development of several biophotonic applications, including spectrally, spatiotemporally resolved, and non-invasive investigations. These advances have also allowed precise and minimally invasive surgical procedures which utilise optical control or appropriate integration with microscopy systems/sensing devises. As a significant number of light-emitting molecules exist in our natural world, particularly in the human body, advanced light sources emitting a range of optical wavelengths have, therefore, been developed to explore various mechanisms in biology, as well as the early detection of a wide array of diseases. Typically, solid-state lasers emitting wavelengths located within the biological optical window have been widely used in imaging and sensing studies. In clinic, miniaturized and user-friendly light sources such as fibre lasers and semiconductor lasers have become a fantastic tool for physicians in both diagnosis and treatment. In recent years, quantum light sources have been developed for metrology, computing, and microscopy imaging, paving a novel route to overcome the limitations exhibited by optical physics. On the other hand, advanced luminescent materials exhibiting the advantages of low-cytotoxicity, biocompatibility, facile surface modification, etc., can be utilized as probes or tracers in high-sensitivity imaging. Furthermore, they have also been applied to bio-sensing systems for determining pH, temperature, gas molecules, inorganic ions, reactive oxygen species, hazardous chemicals, etc., and are of particular significance in biomedical and environmental applications.

The goal of this Research Topic is to collate recent research findings with respect to light sources and luminescent materials for biomedical applications, thereby providing an overview of state-of-the art research in the field. This collection will cover the development of novel light sources for use in both microscopy and spectroscopy. In addition, this collection will provide a platform to gain an enhanced understanding of various luminescent materials and how to utilize them in sensing applications, alongside the promotion of novel research ideas for light-matter interactions in biomedical specimens.

We welcome the submission of Reviews, Mini-Reviews, Perspectives, and Original Research. Topics of interest include, but are not limited to, the following fields:
- The utilization of novel lasers, LEDs, and other light sources for biomedical applications;
- Light sources and luminescent materials seeking to enhance the performance, efficiency, and the wavelength ranges for specific bio-sensing and imaging applications;
- Biocompatible and degradable optical emitters;
- Research pertaining to underlying material research and photophysical mechanisms in life science applications;
- Luminescent Biosensors.

Keywords: olid-state Laser, Semiconductor Laser, Gas Laser, Fiber Laser, Quantum Light Source, Phosphor, Scintillator, Light-emitting Diode, Upconversion Nanoparticle


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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