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Thermophiles are mainly of prokaryotic origin. Advancement of next-generation sequencing, single cell analyses and combinations of omics and microscopic technologies have elevated the scientific discovery of various thermophilic prokaryotes. Several thermophiles that were previously known to be unculturable ...

Thermophiles are mainly of prokaryotic origin. Advancement of next-generation sequencing, single cell analyses and combinations of omics and microscopic technologies have elevated the scientific discovery of various thermophilic prokaryotes. Several thermophiles that were previously known to be unculturable can now be grown in laboratory setups. This Research Topic incorporates reviews, new methods, and extraordinary findings on thermophiles through the tools of omics. The aim of this Research Topic of Frontiers in Microbiology is to provide a platform for researchers to describe single cell sequencing, functional genomics, comparative genomics, cell-cell interactions and evolution from genomic perspective, RNA-Seq, meta-transcriptomic, gene regulation and expression, as well as biostatistics of underexplored thermophiles. We welcome contributions studying thermophiles proteomics and discovery as well as genetic analyses of thermophilic viruses. Investigations of complete genomes of new or common thermophilic bacteria, archaea, or viruses will be considered. High quality draft genomes providing important insights on novel thermophilic strains, newly cultured organisms, or ‘unculturable’ microorganisms, should be submitted as full-scale original research papers.

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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