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Aquaculture, an important industry worldwide, provides edible meat protein for human consumption with an increasing trend in production annually. Having the potential to become a highly sustainable production form, aquaculture has been the fastest growing animal food production sector. However, infectious ...

Aquaculture, an important industry worldwide, provides edible meat protein for human consumption with an increasing trend in production annually. Having the potential to become a highly sustainable production form, aquaculture has been the fastest growing animal food production sector. However, infectious diseases caused by pathogens such as bacteria, viruses, and parasites are major constraints in developing aquaculture, leading to high economic losses and environmental issues.
Efforts in research have been focused on elucidating the host responses against the infection in both model and non-model fish. A thorough understanding of the protective immune response mechanisms in the host would be significantly beneficial for development of new diagnosis methods, treatment and strategies. With the advent of biology molecular technologies, omics approaches are promising tools to understand the response of fish at the levels of genome, transcriptome, proteome, and metabolome to a range of disease infections.

This research topic aims to comprehensively discuss the possible applications of omics technologies and approaches for a better understanding of the immune response mechanisms against infectious diseases in aquaculture fish species. As a consequence of the reduction in the cost of omics analyses, applications of these technologies have been increasingly applied in the aquaculture sector. These approaches allow us to identify and quantify the differential expressed genes, proteins, and metabolites as well as determining their functional structure, revealing a better understanding of the mechanism underlying the fish immune response to pathogens. This research topic is expected to expand the knowledge of fish immune system and immune response mechanism against infectious diseases providing useful basic information for development of biology markers and immune prophylactics strategies in aquaculture.

We welcome the submission of Original Research and Review Articles that cover, but are not limited to, the following sub-topics:
• Omics approaches (transcrptomics, proteomics, metabolomics) in aquaculture to study the fish immune response against pathogens (virus, bacteria, parasites)
• Integrative analysis of multi-omics applied to research on fish diseases
• Development of biological markers associated to disease resistances in fish derived from omics studies.
• Development of vaccine in aquaculture based on omics analyses

Keywords: omics, transcriptomics, proteomics, metabolomics, aquaculture, fish diseases, immune response, fish-pathogen interaction


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