Research Topic

Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

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About this Research Topic

The present Research Topic is based on the following facts:

- Cancer is one of the diseases with higher prevalence and morbi-mortality nowadays.
- Cancer chemotherapy is still greatly feared by the patients (and clinicians) because of the known adverse effects that may occur: nausea, ...

The present Research Topic is based on the following facts:

- Cancer is one of the diseases with higher prevalence and morbi-mortality nowadays.
- Cancer chemotherapy is still greatly feared by the patients (and clinicians) because of the known adverse effects that may occur: nausea, emesis, alterations in blood-cell counting (anaemia, altered immune system and altered clotting), peripheral neuropathy, heart malfunctioning, kidney damage, cognitive loss…
- Current antineoplastic treatments have increased survival and we do not know much yet about the sequelae that they may leave in the survivors: cognitive dysfuntions, cardiovascular alterations, higher risk to gastrointestinal diseases, permanent sensory dysfuntions…
- Current prophylactic treatments to avoid/reduce/treat chemotherapy-induced adverse effects occurring during cycles are not always 100 per cent efficacious (or they may lose efficacy throughout cycles), may not be useful to avoid sequelae, or maybe even add their own side effects to patient discomfort…
- New approaches capable of improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed.

We call authors from all over the world to submit original basic or clinical research or review articles describing the adverse effects of cancer chemotherapy and/or possible new strategies to avoid/reduce these effects, particularly those occurring in the long-term (sequelae), which are still highly unknown.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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