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About this Research Topic

Manuscript Submission Deadline 15 January 2023
Manuscript Extension Submission Deadline 15 February 2023

Acute kidney injury(AKI) is a frequent complication in patients with liver disease and carries a dismal prognosis. The field in AKI is rapidly evolving in cirrhosis with updates on definition, diagnosis, management and assessment of prognosis.

Biomarkers in the field of AKI is also an area of ...

Acute kidney injury(AKI) is a frequent complication in patients with liver disease and carries a dismal prognosis. The field in AKI is rapidly evolving in cirrhosis with updates on definition, diagnosis, management and assessment of prognosis.

Biomarkers in the field of AKI is also an area of unwavering research. There is limited data on biomarkers in the diagnosis and prognosis of AKI in patients with cirrhosis. There is currently an unmet need to gather data on the same. AKI in the context of liver failure whether acute or acute on chronic is a distinct entity and mostly occurs on the background of inflammation and infection. The role of different treatment modalities, use of albumin, terlipressin and renal replacement therapy is particularly sparse. In addition, there is need of more data particularly in the context of AKI transitioning to acute kidney disease and chronic kidney disease and its long term outcomes.

As part of our journal’s mission to address key aspects of gastroenterology, including new avenues for gastroenterological diagnosis, prevention and treatment, Frontiers in Gastroenterology is organizing a Research Topic on “Acute Kidney Injury in Cirrhosis and Liver Failure”. Led by an expert team of editors, the Research Topic will accept all article types within this area of research, with the aim of giving the reader an overview of the latest discoveries and new findings.

Sub-themes for this Research Topic may include, but are not limited to:
- Extracorporeal support therapies for management of AKI
- Multiomics for the diagnosis or prognosis of AKI
- AKI on CKD in cirrhosis
- Post-liver transplant renal dysfunction
- Liver transplant alone versus simultaneous liver-kidney transplant for AKI

Keywords: AKI, liver, kidney, cirrhosis, liver failure, acute kidney injury, nephrology, gastroenterology


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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