About this Research Topic
The unique characteristics of periodontitis and peri-implantitis derive from the anatomy of the periodontium or the peri-implant region, as hard and non-shedding structures (tooth and implant) are partially embedded in the body and partially facing outwards (oral cavity). When this interface is colonized by bacteria and biofilm control is not efficient, the process of dysbiosis arises. However, it is the way an individual responds to these bacteria, rather than the bacteria themselves, that determines the expression the subsequent disease progression. All of this can still be modified by systemic, environmental and genetic risk factors.
Many of these particularities of periodontal and peri-implant disease have been understood through preclinical studies, as they are an important stage in research and provide information regarding the pathogenesis and treatment of diseases. Due to these studies, our understanding on the role of the biofilm and the immunoinflammatory response in the development and progression of periodontal disease and, more recently, peri-implantitis could reach a high level of knowledge, providing a fundamental basis for further clinical studies.
This Research Topic aims to present the best scientific evidences regarding preclinical studies in order to improve our knowledge about disease progression, periodontal/peri-implant defects, treatment and periodontal medicine.
The scope of this Research Topic includes (but are not limited to) preclinical studies in the following areas:
• Experimental periodontitis or peri-implantitis models
• Immune inflammatory response to oral biofilms
• Effects of treatment on the inflammatory response against periodontopathogens.
• The link between periodontal disease and systemic health
• Novel therapies for the management of periodontitis or peri-implantitis
Many of these particularities of periodontal and peri-implant disease have been understood through preclinical studies, as they are an important stage in research and provide information regarding the pathogenesis and treatment of diseases. Due to these studies, our understanding on the role of the biofilm and the immunoinflammatory response in the development and progression of periodontal disease and, more recently, peri-implantitis could reach a high level of knowledge, providing a fundamental basis for further clinical studies.
This Research Topic aims to present the best scientific evidences regarding preclinical studies in order to improve our knowledge about disease progression, periodontal/peri-implant defects, treatment and periodontal medicine.
The scope of this Research Topic includes (but are not limited to) preclinical studies in the following areas:
• Experimental periodontitis or peri-implantitis models
• Immune inflammatory response to oral biofilms
• Effects of treatment on the inflammatory response against periodontopathogens.
• The link between periodontal disease and systemic health
• Novel therapies for the management of periodontitis or peri-implantitis
Keywords: Periodontitis, Peri-implantitis, Disease management, Biofilms, Inflammatory response, Preclinical studies, Periodontal disease, Systemic health, Therapeutics, Disease progression, Tooth implant, Periodontal defects, Peri-implant defects
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
