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Manuscript Submission Deadline 20 January 2023
Manuscript Extension Submission Deadline 19 February 2023

Liquid biphasic reaction systems are of great interests among both basic laboratory synthesis and practical industrial processes, which has triggered substantial efforts in developing new protocols for their efficient applications. Recently, the development of new mobile phase, such as ionic liquids, supercritical fluids, and fluorous solvents, has induced renaissance in liquid biphasic research and opened new windows for novel biphasic reaction system design, which will significantly extend the scope of liquid biphasic systems. While liquid biphasic reaction systems offer promising solutions to sustainable manufacturing that features possible catalyst recycling, easy product separation, and improved reaction selectivity, the systems also suffer from slow reaction kinetics resulted from limited mass and heat transport which results in extensive usage of energy and solvents. In this case, an in-depth understanding of the kinetics at the liquid-liquid interface is crucial for more efficient liquid biphasic action system design.

There is an essential need for process intensification in various liquid biphasic reaction systems to overcome mass and heat transfer limitation, to increase reaction kinetics, to understand interfacial phenomena, thus to design efficient liquid biphasic reaction systems for sustainable applications in chemical industry. The aim of the research topic is therefore to cover some of the recent research highlights, trends, and challenges in this field to gain fundamental and in-depth understanding of the interfacial phenomena in the wide interdisciplinary area of liquid biphasic reaction system, thus to provide comprehensive mechanistic insights and to trigger further efforts on the development of novel biphasic reaction systems for sustainable chemistry.

We invite original research articles, reviews, mini-reviews, and perspectives in this research topic on but not limited to:

• Novel devices, reactors, and processes design for process intensification in liquid biphasic systems
• Design, application, and mechanistic studies of liquid biphasic catalysts
• Discovery of new solvent systems
• Fundamental investigation on liquid interfacial phenomena and reaction characteristics
• Modeling and simulation of liquid biphasic reaction systems
• Strategies and techniques in system monitoring and characterization
• Liquid biphasic system engineering
• Novel or potential applications of liquid biphasic reaction systems in current chemical industry

Keywords: Process Intensification, Liquid Biphasic Reaction Systems, Reactors Design, Processes Design, Liquid Biphasic Reactions, Solvent Systems, Modeling Biphasic Reactions


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Liquid biphasic reaction systems are of great interests among both basic laboratory synthesis and practical industrial processes, which has triggered substantial efforts in developing new protocols for their efficient applications. Recently, the development of new mobile phase, such as ionic liquids, supercritical fluids, and fluorous solvents, has induced renaissance in liquid biphasic research and opened new windows for novel biphasic reaction system design, which will significantly extend the scope of liquid biphasic systems. While liquid biphasic reaction systems offer promising solutions to sustainable manufacturing that features possible catalyst recycling, easy product separation, and improved reaction selectivity, the systems also suffer from slow reaction kinetics resulted from limited mass and heat transport which results in extensive usage of energy and solvents. In this case, an in-depth understanding of the kinetics at the liquid-liquid interface is crucial for more efficient liquid biphasic action system design.

There is an essential need for process intensification in various liquid biphasic reaction systems to overcome mass and heat transfer limitation, to increase reaction kinetics, to understand interfacial phenomena, thus to design efficient liquid biphasic reaction systems for sustainable applications in chemical industry. The aim of the research topic is therefore to cover some of the recent research highlights, trends, and challenges in this field to gain fundamental and in-depth understanding of the interfacial phenomena in the wide interdisciplinary area of liquid biphasic reaction system, thus to provide comprehensive mechanistic insights and to trigger further efforts on the development of novel biphasic reaction systems for sustainable chemistry.

We invite original research articles, reviews, mini-reviews, and perspectives in this research topic on but not limited to:

• Novel devices, reactors, and processes design for process intensification in liquid biphasic systems
• Design, application, and mechanistic studies of liquid biphasic catalysts
• Discovery of new solvent systems
• Fundamental investigation on liquid interfacial phenomena and reaction characteristics
• Modeling and simulation of liquid biphasic reaction systems
• Strategies and techniques in system monitoring and characterization
• Liquid biphasic system engineering
• Novel or potential applications of liquid biphasic reaction systems in current chemical industry

Keywords: Process Intensification, Liquid Biphasic Reaction Systems, Reactors Design, Processes Design, Liquid Biphasic Reactions, Solvent Systems, Modeling Biphasic Reactions


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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