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Metal cations, anions, and small biomolecules are widely distributed in environmental and biological systems. The content of ions and small molecules is closely related to their functions in the environment and biological systems. Metal cations like Hg2+, Cd2+, and Pd species, have ...

Metal cations, anions, and small biomolecules are widely distributed in environmental and biological systems. The content of ions and small molecules is closely related to their functions in the environment and biological systems. Metal cations like Hg2+, Cd2+, and Pd species, have increased with industrialization, mandating their measurement in environmental and biological systems. Metal cations including Cu+/Cu2+, Fe2+/Fe3+, Zn2+, and Na+ are essential for normal biological processes, and dysregulation of homeostasis of these ions may cause various diseases. Similarly, a number of anions including cyanide and fluoride are toxic, and the imbalance of phosphate ions is closely related to arthritis, osteoporosis, hypophosphatemia, and so on. The imbalance of cations and anions can cause changes in the content and distribution of various small molecules, such as ATP, amino acids, glucose, and urea, et. al., in various organisms. Accurate monitoring of the biomolecular changes in biological and physiological environments is important for diagnosing and treating diseases caused by ion imbalances.

The goal of this topic is to explore and obtain advanced functional molecules and materials for the fast, simple, sensitive, cheap, and highly selective detection of cations, anions, and small biomolecules in the environment and living systems. This article collection aims to shed light on the most advanced achievements in the relationship between ions, environment, and living organisms, which should inspire and guide the future direction of this field.

The scope of the Research Topic includes cations, anions, and small biomolecules related to separation, detection, and imaging. Areas to be covered in this Research Topic may include, but are not limited to:
● New functional molecules and materials for the detection of cations, anions, and small biomolecules;
● New methods for the detection of cations, anions, and small biomolecules;
● New signals for the detection of cations, anions, and small biomolecules;
● New discoveries about the relationship between ions, environment, and living systems;
● New functional molecules and materials for adsorption and removal of cations, anions, and small biomolecules.

Keywords: biomolecules, dysregulation of homeostasis, metal cations, anions, ion imbalance


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