Atherosclerosis (AS) is a chronic progressive inflammatory disease involving the lipid deposition and is the common pathological basis of many cardiovascular diseases. Cardiovascular events such as stroke, coronary heart disease and myocardial infarction resulted from AS have become a serious threat to human health. Therefore, it will be significant to understand the pathogenesis of AS and explore novel therapeutic strategies for AS and its cardiovascular complications.
Atherosclerotic plaque formation and stability play an important role in atherosclerotic cardiovascular diseases. The foam cell formation and its accumulation in arterial intima trigger a series of inflammatory response, leading to atherosclerotic plaque formation. However, the regulatory mechanism of foam cell formation during atherosclerosis remains incompletely understood. We hope to take insight into more innovative scientific discoveries about foam cell formation involving AS therapy and to guide the clinical application in the future.
This Research Topic is committed to accepting high-quality original research, review, and commentary articles linking new regulatory mechanisms, therapeutic strategies and molecular markers for foam cell formation, lipid metabolism, vascular inflammation and aims to provide more effective prevention and treatment for atherosclerosis and cardiovascular diseases in clinic.
We welcome new targets research, pre-clinical research, clinical trials, and novel drugs on the following topics, but are not limited to:
- Cellular and molecular mechanisms of macrophage/VSMC-derived foam cell formation in atherosclerosis.
- Cellular and molecular mechanisms of vascular cell function in atherosclerosis.
- From basic to clinical application - clinical translational research in foam cells formation and atherosclerosis diseases.
- The potential therapeutic strategies regarding foam cell and inflammation in the prevention of atherosclerosis.
- Molecular mechanisms of hyperlipidemia and reverse cholesterol transport during atherosclerosis.
- Research on new drugs for the treatment of foam cell formation and atherosclerosis.
- Analysis of risk factors related to foam cell formation, hyperlipidemia and atherosclerosis.
Atherosclerosis (AS) is a chronic progressive inflammatory disease involving the lipid deposition and is the common pathological basis of many cardiovascular diseases. Cardiovascular events such as stroke, coronary heart disease and myocardial infarction resulted from AS have become a serious threat to human health. Therefore, it will be significant to understand the pathogenesis of AS and explore novel therapeutic strategies for AS and its cardiovascular complications.
Atherosclerotic plaque formation and stability play an important role in atherosclerotic cardiovascular diseases. The foam cell formation and its accumulation in arterial intima trigger a series of inflammatory response, leading to atherosclerotic plaque formation. However, the regulatory mechanism of foam cell formation during atherosclerosis remains incompletely understood. We hope to take insight into more innovative scientific discoveries about foam cell formation involving AS therapy and to guide the clinical application in the future.
This Research Topic is committed to accepting high-quality original research, review, and commentary articles linking new regulatory mechanisms, therapeutic strategies and molecular markers for foam cell formation, lipid metabolism, vascular inflammation and aims to provide more effective prevention and treatment for atherosclerosis and cardiovascular diseases in clinic.
We welcome new targets research, pre-clinical research, clinical trials, and novel drugs on the following topics, but are not limited to:
- Cellular and molecular mechanisms of macrophage/VSMC-derived foam cell formation in atherosclerosis.
- Cellular and molecular mechanisms of vascular cell function in atherosclerosis.
- From basic to clinical application - clinical translational research in foam cells formation and atherosclerosis diseases.
- The potential therapeutic strategies regarding foam cell and inflammation in the prevention of atherosclerosis.
- Molecular mechanisms of hyperlipidemia and reverse cholesterol transport during atherosclerosis.
- Research on new drugs for the treatment of foam cell formation and atherosclerosis.
- Analysis of risk factors related to foam cell formation, hyperlipidemia and atherosclerosis.
