About this Research Topic
Frontiers in Aging Neuroscience has organized a series of Research Topics which aim to promote discussion or to change the perspective on experimental and clinical research in various areas of the field of neuroscience.
In this Research Topic, we will aim to deepen our understanding of the relationship between Lewy bodies and mood disorders. Lewy body dementia can be challenging to diagnose as the symptoms of the disease are often similar to other neurological disorders in the elderly. The similarity in symptoms can lead to the disorder being misdiagnosed or not correctly diagnosed until it is in the later stages. One of the early symptoms of Lewy body dementia is a change in mood. Abnormal deposits of alpha-synuclein, associated with Lewy body dementia, can contribute to these changes in mood and thinking, although it is unknown why these deposits develop.
Lewy body dementia often occurs in individuals who do not have a family history of the disease, which contributes to our lack of understanding of the development of the disorder. Additionally, there is no cure for this type of dementia. The combination of these facts exacerbates the need for further research in this field. We would therefore like to investigate the relationship between Lewy bodies and mood disorders in the elderly to understand the relevance of mood disorders as an early symptom of dementia and to see if this could ultimately lead to preventative action.
To provide a critical evaluation of the state of research in the field of Lewy Bodies and Mood Disorders in the Elderly, leading experts have been invited by our Topic Editors to contribute their thoughts and perspectives on current challenges, latest discoveries, recent technological advances, and future directions in the field.
This Research Topic solicits the submission of Opinion and Perspective articles that provide editorialized analysis related to the field of Alzheimer's Disease and Related Dementias by established researchers in the field.
Please note that Abstract submission is strongly recommended.
In this Research Topic, we will aim to deepen our understanding of the relationship between Lewy bodies and mood disorders. Lewy body dementia can be challenging to diagnose as the symptoms of the disease are often similar to other neurological disorders in the elderly. The similarity in symptoms can lead to the disorder being misdiagnosed or not correctly diagnosed until it is in the later stages. One of the early symptoms of Lewy body dementia is a change in mood. Abnormal deposits of alpha-synuclein, associated with Lewy body dementia, can contribute to these changes in mood and thinking, although it is unknown why these deposits develop.
Lewy body dementia often occurs in individuals who do not have a family history of the disease, which contributes to our lack of understanding of the development of the disorder. Additionally, there is no cure for this type of dementia. The combination of these facts exacerbates the need for further research in this field. We would therefore like to investigate the relationship between Lewy bodies and mood disorders in the elderly to understand the relevance of mood disorders as an early symptom of dementia and to see if this could ultimately lead to preventative action.
To provide a critical evaluation of the state of research in the field of Lewy Bodies and Mood Disorders in the Elderly, leading experts have been invited by our Topic Editors to contribute their thoughts and perspectives on current challenges, latest discoveries, recent technological advances, and future directions in the field.
This Research Topic solicits the submission of Opinion and Perspective articles that provide editorialized analysis related to the field of Alzheimer's Disease and Related Dementias by established researchers in the field.
Please note that Abstract submission is strongly recommended.
Keywords: Lewy Bodies, Mood Disorders, Alzheimer's Disease
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
