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Manuscript Submission Deadline 01 June 2023
Manuscript Extension Submission Deadline 01 July 2023

Bioactive glasses are one of the most prominent classes of biomaterials and are widely employed in various fields of regenerative medicine, in particular for the repair and regeneration of hard tissues such as bone and dental structures, as well as soft tissues like heart, nerve, lung and skin. This diverse range of applications is possible due to their superior biocompatibility, bioactivity, degradability, cell viability, reduced cytotoxicity, enhanced antimicrobial activity, osteogenesis and angiogenesis properties when compared to other biomaterials. Bioactive glasses are surface reactive materials when they are in contact with physiological fluids, such as human plasma, or other aqueous solutions. This surface bioreactivity enables strong bonding with the surrounding bone and other tissues, which gives bioglasses their osteoconductive properties. Likewise, there are other attractive properties of these glasses which widen their applications in the biomedical domain.

Bioglass is gaining tremendous incentive due to its ability in repair and regeneration of both soft and hard tissues when compared with other biomaterials. Although there has been constant advancement in this field, a variety of challenges still persist for their effective translation into therapeutics. In order to bridge such gaps, new bioglass materials need to be systematically developed with enhanced functionalities. Researchers should look towards the development of various types and forms of bio-mimetic novel bioglass materials in order to cater to the high demand in biomedicine, where the damage of human tissues by infectious diseases or other means is a pressing problem requiring immediate attention.

This Research Topic aims to promote advancement in the field of bioglasses and their enhanced functionality for streamlined tissue engineering applications. Accordingly, all types of articles on such biomedical, biomaterial, and multidisciplinary studies bordering the associated domains are particularly encouraged. Authors are kindly invited to submit effective contributions on bioactive glass materials such as bioglass ceramics, bioglass composites, mesoporous and microporous bioglasses/composites, and other areas that address (but are not limited to) the following topics:

• Bioactive glasses activated by therapeutic ions for bone repair and regeneration applications
• Transition metal-doped glass ceramics for dental implants and treatment
• Mesoporous bioglass composites for drug delivery applications
• Bioglasses as toothpaste ingredients (eg, Dentin repair and regeneration)
• Bioglass coatings for soft tissue implants and surgical devices
• Anti-microbial, anti-inflammatory, anti-diabetic, anti-cancer and other bioactivity enhancement in bioglasses
• Surface modification, processing and bio-mechanics of bioglasses, bio-nanocomposites, nano-engineering and bioglass-based hydrogels/ other biomaterials

Keywords: Bioactive Glass, Tissue Engineering, Drug Delivery, Scaffolds, Implants, Osteogenesis, angiogenesis


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Bioactive glasses are one of the most prominent classes of biomaterials and are widely employed in various fields of regenerative medicine, in particular for the repair and regeneration of hard tissues such as bone and dental structures, as well as soft tissues like heart, nerve, lung and skin. This diverse range of applications is possible due to their superior biocompatibility, bioactivity, degradability, cell viability, reduced cytotoxicity, enhanced antimicrobial activity, osteogenesis and angiogenesis properties when compared to other biomaterials. Bioactive glasses are surface reactive materials when they are in contact with physiological fluids, such as human plasma, or other aqueous solutions. This surface bioreactivity enables strong bonding with the surrounding bone and other tissues, which gives bioglasses their osteoconductive properties. Likewise, there are other attractive properties of these glasses which widen their applications in the biomedical domain.

Bioglass is gaining tremendous incentive due to its ability in repair and regeneration of both soft and hard tissues when compared with other biomaterials. Although there has been constant advancement in this field, a variety of challenges still persist for their effective translation into therapeutics. In order to bridge such gaps, new bioglass materials need to be systematically developed with enhanced functionalities. Researchers should look towards the development of various types and forms of bio-mimetic novel bioglass materials in order to cater to the high demand in biomedicine, where the damage of human tissues by infectious diseases or other means is a pressing problem requiring immediate attention.

This Research Topic aims to promote advancement in the field of bioglasses and their enhanced functionality for streamlined tissue engineering applications. Accordingly, all types of articles on such biomedical, biomaterial, and multidisciplinary studies bordering the associated domains are particularly encouraged. Authors are kindly invited to submit effective contributions on bioactive glass materials such as bioglass ceramics, bioglass composites, mesoporous and microporous bioglasses/composites, and other areas that address (but are not limited to) the following topics:

• Bioactive glasses activated by therapeutic ions for bone repair and regeneration applications
• Transition metal-doped glass ceramics for dental implants and treatment
• Mesoporous bioglass composites for drug delivery applications
• Bioglasses as toothpaste ingredients (eg, Dentin repair and regeneration)
• Bioglass coatings for soft tissue implants and surgical devices
• Anti-microbial, anti-inflammatory, anti-diabetic, anti-cancer and other bioactivity enhancement in bioglasses
• Surface modification, processing and bio-mechanics of bioglasses, bio-nanocomposites, nano-engineering and bioglass-based hydrogels/ other biomaterials

Keywords: Bioactive Glass, Tissue Engineering, Drug Delivery, Scaffolds, Implants, Osteogenesis, angiogenesis


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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