Microbiome Imbalance In Tropical Areas

The human microbiome has emerged as an important agent in the interactions between the body and infectious pathogens. Indeed, it is recognized that the microbiome can influence humans’ mental and health status, or switch on several diseases (e.g., cancer, cardio-metabolic diseases, allergies, autoimmunities, and obesity). Since the majority of immune cells are present in the gut, the microbiome is acknowledged to play a crucial role in local immune response and systemic immunity to pathogens and infectious diseases, which remain a leading cause of death in tropical areas of the world. Given the burden posed by such diseases to this day, it is important to develop a better understanding of the connection between the microbiome, which can be influenced through nutrition, and tropical pathogens as well as the health outcomes of populations in these parts of the world.

This Research Topic therefore aims to present studies on the human microbiome and its interplay with tropical diseases and infectious pathogens, with the role of nutrition being an additional aspect that could also be explored in some of these works. Original research, reviews, mini-reviews and other article types accepted by Frontiers focusing on the interplay between infectious diseases and the microbiome in tropical areas are welcome.