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About this Research Topic

Manuscript Submission Deadline 31 July 2023

Human teeth are a very complex and multi-faceted organ, the study of which comprises the elucidation of several aspects, including morphology, macromolecular and chemical composition, mechanical and functional properties, as well as interaction with different biomaterials.

Several analytical techniques, including Scanning Electron Microscopy, X-ray diffraction, and Energy Dispersive X-ray Spectroscopy, have been individually applied to elucidate specific issues in dentistry. Recently, new high-resolution techniques, including vibrational spectroscopies, such as Infrared and Raman spectroscopies, and Microcomputed Tomography (µ-CT), have been introduced. These latter analytical tools have the advantage to preserve the sample without destroying it, since they do not require fixing procedures before measurements, which could influence the final analysis. Moreover, the last generation of Infrared and Raman spectrometers are coupled with optical microscopes and can obtain reliable and objective information both on the chemical composition and the structure of the sample, on the same samples and at the same time. This is allows for the simplification of data acquisition and reduces times of analysis.

On these bases, it appears evident that the coupling of these high-resolution techniques in a multidisciplinary approach represents a valuable tool to obtain reliable and comprehensive information at a molecular level on the micro- and macro-structure of sound and pathological dental tissues and on the structural properties of new generation biomaterials. This is advantageous for improving the diagnosis and treatment of several dental pathologies. Furthermore, shedding new light on the design and development of innovative dental materials will clarify their interaction with hard dental tissues, thus suggesting non-invasive and more appropriate simplified clinical protocols both in primary and permanent teeth.

Based on the exposed, the goal of this Research Topic is to provide a platform for clinicians and researchers to present and share significant findings on dental tissues and innovative biomaterials characterization. For this purpose, this Research Topic aims to include up-to-date high-resolution analytical techniques which help advance in this topic.

We seek original research articles, review, mini-reviews, perspectives and brief research reports that may include (but not limited to):

- Deep analysis, based on high resolution techniques, of dental tissues, both in primary and permanent teeth;

- Deep analysis, based on high resolution techniques, of dental biomaterials;

- Deep analysis of the interaction between dental tissues and biomaterials, such as the efficacy of remineralizing agents, future perspective of resin-based dental materials.

Keywords: High resolution techniques, dental tissues, primary teeth, permanent teeth, Vibrational spectroscopies, µ-CT, SEM, dental materials, remineralizing agents, resin-based composites


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Human teeth are a very complex and multi-faceted organ, the study of which comprises the elucidation of several aspects, including morphology, macromolecular and chemical composition, mechanical and functional properties, as well as interaction with different biomaterials.

Several analytical techniques, including Scanning Electron Microscopy, X-ray diffraction, and Energy Dispersive X-ray Spectroscopy, have been individually applied to elucidate specific issues in dentistry. Recently, new high-resolution techniques, including vibrational spectroscopies, such as Infrared and Raman spectroscopies, and Microcomputed Tomography (µ-CT), have been introduced. These latter analytical tools have the advantage to preserve the sample without destroying it, since they do not require fixing procedures before measurements, which could influence the final analysis. Moreover, the last generation of Infrared and Raman spectrometers are coupled with optical microscopes and can obtain reliable and objective information both on the chemical composition and the structure of the sample, on the same samples and at the same time. This is allows for the simplification of data acquisition and reduces times of analysis.

On these bases, it appears evident that the coupling of these high-resolution techniques in a multidisciplinary approach represents a valuable tool to obtain reliable and comprehensive information at a molecular level on the micro- and macro-structure of sound and pathological dental tissues and on the structural properties of new generation biomaterials. This is advantageous for improving the diagnosis and treatment of several dental pathologies. Furthermore, shedding new light on the design and development of innovative dental materials will clarify their interaction with hard dental tissues, thus suggesting non-invasive and more appropriate simplified clinical protocols both in primary and permanent teeth.

Based on the exposed, the goal of this Research Topic is to provide a platform for clinicians and researchers to present and share significant findings on dental tissues and innovative biomaterials characterization. For this purpose, this Research Topic aims to include up-to-date high-resolution analytical techniques which help advance in this topic.

We seek original research articles, review, mini-reviews, perspectives and brief research reports that may include (but not limited to):

- Deep analysis, based on high resolution techniques, of dental tissues, both in primary and permanent teeth;

- Deep analysis, based on high resolution techniques, of dental biomaterials;

- Deep analysis of the interaction between dental tissues and biomaterials, such as the efficacy of remineralizing agents, future perspective of resin-based dental materials.

Keywords: High resolution techniques, dental tissues, primary teeth, permanent teeth, Vibrational spectroscopies, µ-CT, SEM, dental materials, remineralizing agents, resin-based composites


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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