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About this Research Topic

Manuscript Submission Deadline 21 May 2023
Manuscript Extension Submission Deadline 20 June 2023

Viral infection encompasses a complex interplay between virus-associated factors and the host immune responses shaping up the disease progression. Effective immune response not only causes viral clearance by the protective anti-viral response but also controls the inflammatory process to prevent tissue injury ...

Viral infection encompasses a complex interplay between virus-associated factors and the host immune responses shaping up the disease progression. Effective immune response not only causes viral clearance by the protective anti-viral response but also controls the inflammatory process to prevent tissue injury and damage, as host survival depends on this delicate balance. Immune response regulation and activating effector antimicrobial pathway are driven by the purinergic system that performs this dual function.

The goal of this Research Topic is to improve the knowledge and understanding of the immunological aspects of innate and adaptive immune modulation driven by the purinergic system during viral infections. All submissions pertaining to the latest knowledge elucidating the role of the purinergic system in viral clearance or in the control of inflammatory processes related to viral, infection will be given full consideration for publication.

This Research Topic aims to publish Review articles, Original Research papers, commentaries, opinions, and perspective articles focusing on the immunological aspects of the purinergic system’s dual role in infections caused by viruses. Sub-themes revolving around the main topic will be included, but are not limited to, the following:

• Purinergic signaling cascade triggered exclusively by viruses.

• Work on modulation of the infectious disease process by purinergic receptor inhibition.

• Novel drug targets with reference to the prevention of infectious diseases and the purinergic system.

• Interplay between purinergic signaling and inflammation.

Keywords: Purinergic system, Adaptive immunity, Innate Immunity, Immuno-modulation, viral Infections


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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