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About this Research Topic

Manuscript Submission Deadline 31 January 2024

Obesity, or excess fat deposition, is a known risk factor for hypertension, hyperlipidemia, and type 2 diabetes. Excess visceral adiposity has an independent, detrimental impact on various cardio-metabolic diseases. Adipocyte turnover in the visceral cavity also influences circulating levels of fatty acids, ...

Obesity, or excess fat deposition, is a known risk factor for hypertension, hyperlipidemia, and type 2 diabetes. Excess visceral adiposity has an independent, detrimental impact on various cardio-metabolic diseases. Adipocyte turnover in the visceral cavity also influences circulating levels of fatty acids, lipoproteins, and adipocytokines, which could cross the blood-brain barrier and disrupt cellular signaling homeostasis, synaptic plasticity and memory, and maintenance of various neuronal cells.

Both genetic predisposition and environmental-lifestyle factors contribute to population variance in excess visceral fat deposition. Recent findings in multi-omics have expanded our understanding of the impact of dietary intake on our health. However, how eating behavior drives dietary patterns and quality remains to be fully understood; for example, one of the depressive symptoms is both poor appetite and over-eating, but what drives such extremely diverse outcomes (under vs. over-eating) is unclear.

This Research Topic aims to curate the latest evidence on the impact of eating behavior on adiposity and cardiometabolic health, in the form of Original Research, Short Communication and Systematic Reviews. Eating behavior includes, but is not limited to appetite, dietary pattern, taste preference, stress-eating, meal pattern, and controlled eating. We especially welcome:
• Epidemiological studies and randomized controlled trials focusing on providing evidence of causality in multi-ethnic, less European-centric subpopulations
• Studies with state-of-the-art multi-omics to unravel the underlying biological mechanisms
• Epidemiological studies and randomized controlled trials with high-throughput measurement of neuropeptides and/or brain imaging to unravel underlie biological mechanisms.

Keywords: Eating Behavior, adiposity, cardiometabolic health, neurobiology


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