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Ticks are the vector of a wide variety of infectious agents, such as spirochetes, protozoa, bacteria, and viruses. Tick-borne diseases are numerous and have a substantial impact on human and animal health. Traditionally, studies over the last decade have focused on the morphological identification of ticks, ...

Ticks are the vector of a wide variety of infectious agents, such as spirochetes, protozoa, bacteria, and viruses. Tick-borne diseases are numerous and have a substantial impact on human and animal health. Traditionally, studies over the last decade have focused on the morphological identification of ticks, their life cycle, and the epidemiology of tick-borne pathogens. There has been a great deal of advancements in research focusing on the interactions of these pathogens with the vectors capable of transmission to a vertebrate host. However, no effective vaccines nor limited drugs are available at the present for ticks and tick-borne diseases. This Research Topic aims to contribute to a better understanding of the transmission of pathogen interactions between arthropod vectors and the vertebrate hosts.
The goal of this Research Topic is to explore the biological mechanisms involved in pathogens-tick and pathogens-host interactions. The complex transmission mechanisms of different pathogens are the main reason for the challenges in tick-borne disease prevention and control. Therefore, the identification and characterization of specific molecules is extremely important for the development of future vaccines against vector-borne diseases. This Research Topic welcomes manuscripts that focus on new strategies for the control and eradication of tick-borne diseases, including (but not limited to) the following topics:
• Omics analysis of tick and tick-borne diseases, including any of the ‘omics’-related research that lends insight into tick-pathogen relationships.
• Biomarkers discoveries for novel diagnostic strategies and effective tick-borne disease prevention.
• Research involving tick-animal and host-pathogens relationships and biological mechanisms related to ticks and tick-borne pathogens, including hard and soft ticks.
• Development of an animal host model to understand pathogen transmission from tick vectors.

Keywords: Tick, Pathogen-tick interactions, Pathogenesis, Molecular biology, Prevention


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