About this Research Topic
Arboviruses are a group of viruses that are transmitted to susceptible vertebrates through the bite of blood-sucking arthropods. The vectors include mosquitoes, ticks, culicoides, midges, sandy flies, and gnats, with mosquitoes and ticks being the most important. There are 537 species of arboviruses registered in the International Center, belonging to at least 20 virus families. Among them, arboviruses closely related to human and animal diseases are mainly distributed in Flaviviridae, Reoviridae, Togaviridae, Panbunyaviridae, Leucoviridae, and Neiroviridae. According to the World Health Organization, Dengue virus (DENV) infects about 390 million people annually in 130 endemic countries. Yellow fever, caused by yellow fever virus (YFV), poses a high risk of outbreaks in 40 countries, causing jaundice and severe hemorrhagic fever and even death. Chikungunya virus (CHIKV)has now been identified in 115 countries in Asia, Africa, Europe and the Americas and can cause severe crippling arthritis. Zika virus (ZIKV) infection gained widespread attention worldwide in 2016 when it was found to cause birth defects such as microcephaly, and to date, ZIKV has been recorded to be transmitted by autochthonous mosquitoes in 87 countries and regions. Japanese Encephalitis Virus (JEV) infects about 68,000 people and causes about 13,600-20,400 deaths yearly, with approximately 3 billion people living in JEV epidemic areas.
Due to high urbanization, climate change and increased travel, the frequency and magnitude of outbreaks of arboviruses are continuously increasing worldwide, posing a serious challenge to world public health. Currently, most arboviral diseases lack effective drugs and vaccines, and passive control measures can only be taken after the outbreak. Understanding the molecular genetics, phylogeny, origin and evolution, pathogenesis and diagnosis of arboviruses would be of great significance for the control and prevention of arbovirus disease.
This research topic focuses on the extensive and in-depth discussion of arboviruses that pose serious threats or potential risks to human and animal life and health, including but not limited to genomics, molecular genetics, phylogeny and evolution, spatio-temporal dynamics, pathogenesis, and diagnostic development, to better understand its transmission direction and pathogenic mechanism. It is of great significance for the prevention and treatment of arbovirus diseases. We invite contributions of Original Research, Methods, Review, Mini Review, Hypothesis and Theory and Perspective covering the following topics of interest:
1. Identification and Molecular genetic characteristics of Arbovirus
2. Diversity, evolution, phylogenetics and epidemiology of Arbovirus
3. Pathogenesis of arbovirus diseases.
4. Advance in molecular and serological assays for the detection of arboviruses
Due to high urbanization, climate change and increased travel, the frequency and magnitude of outbreaks of arboviruses are continuously increasing worldwide, posing a serious challenge to world public health. Currently, most arboviral diseases lack effective drugs and vaccines, and passive control measures can only be taken after the outbreak. Understanding the molecular genetics, phylogeny, origin and evolution, pathogenesis and diagnosis of arboviruses would be of great significance for the control and prevention of arbovirus disease.
This research topic focuses on the extensive and in-depth discussion of arboviruses that pose serious threats or potential risks to human and animal life and health, including but not limited to genomics, molecular genetics, phylogeny and evolution, spatio-temporal dynamics, pathogenesis, and diagnostic development, to better understand its transmission direction and pathogenic mechanism. It is of great significance for the prevention and treatment of arbovirus diseases. We invite contributions of Original Research, Methods, Review, Mini Review, Hypothesis and Theory and Perspective covering the following topics of interest:
1. Identification and Molecular genetic characteristics of Arbovirus
2. Diversity, evolution, phylogenetics and epidemiology of Arbovirus
3. Pathogenesis of arbovirus diseases.
4. Advance in molecular and serological assays for the detection of arboviruses
Keywords: Molecular Genetics, Arboviruses, Pathogenesis, Diagnosis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
